Sökning: "pyridyl alcohol"

Hittade 3 avhandlingar innehållade orden pyridyl alcohol.

  1. 1. Chiral Pyridine-Containing Ligands for Asymmetric Catalysis. Synthesis and Applications

    Författare :Fredrik Rahm; KTH; []
    Nyckelord :asymmetric catalysis; chiral ligand; chiral pool; oxazoline; crown ether; ditopic receptor; bipyridine; pyridyl alcohol; modular approach; P; N-ligand; diethylzinc; allylic alkylation;

    Sammanfattning : This thesis deals with the design and syntheses of chiral,enantiopure pyridinecontaining ligands and their applicationsin asymmetric catalyis.Chiral pyridyl pyrrolidine ligands and pyridyl oxazolineligands were synthesized and employed in thepalladium-catalysed allylic alkylation of 1,3-diphenyl-2-propenyl acetate with dimethyl malonate. LÄS MER

  3. 2. Design and Synthesis of Novel HIV-1 Protease Inhibitors Comprising a Tertiary Alcohol in the Transition-State Mimic

    Författare :Jenny Ekegren; Anders Hallberg; Daniel Rich; Uppsala universitet; []
    Nyckelord :Chemistry; HIV AIDS; HIV-1 protease inhibitor; transition-state mimic; tertiary alcohol; palladium; cross-coupling; aminocarbonylation; microwave; molybdenum hexacarbonyl; Kemi;

    Sammanfattning : HIV-1 protease inhibitors are important in the most frequently used regimen for the treatment of HIV/AIDS, the highly active antiretroviral therapy (HAART). For patients with access to this treatment, an HIV infection is no longer lethal, but rather a manageable, chronic infection. LÄS MER

  4. 3. Toxicity of smokeless tobacco in human oral epithelium with emphasis on carcinogen metabolism and regulation of programmed cell death

    Författare :Martin Vondracek; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The oral mucosa is globally a common site for cancer development. Primary risk factors include tobacco smoking and alcohol consumption whereas the contribution from usage of smokeless tobacco remains debated. LÄS MER