Sökning: "protein superfamily"

Visar resultat 1 - 5 av 157 avhandlingar innehållade orden protein superfamily.

  1. 1. Structural Information and Hidden Markov Models for Biological Sequence Analysis

    Författare :Jeanette Tångrot; Bo Kågström; Uwe H. Sauer; Erik Sonnhammer; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; HMM; structure alignment; protein structure; secondary structure; remote homologue; annotation; domain family; protein family; protein superfamily; protein fold recognition; Bioinformatics; Bioinformatik;

    Sammanfattning : Bioinformatics is a fast-developing field, which makes use of computational methods to analyse and structure biological data. An important branch of bioinformatics is structure and function prediction of proteins, which is often based on finding relationships to already characterized proteins. LÄS MER

  3. 2. Bioinformatic protein family characterisation

    Författare :Joel Hedlund; Bengt Persson; Jaap Heringa; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : Biological research is necessary; not only to further our understanding of the processes of life, but also to combat disease, hunger and environmental damage.Bioinformatics is the science of handling biological information. It entails integrating, structuring and analysing the ever-increasing amounts of available biological data. LÄS MER

  4. 3. Bioinformatic methods in protein characterization

    Författare :Yvonne Kallberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Bioinformatic methods in protein characterization;

    Sammanfattning : Bioinformatics is an emerging interdisciplinary research field in which mathematics. computer science and biology meet. In this thesis. bioinformatic methods for analysis of functional and structural properties among proteins will be presented. LÄS MER

  5. 4. Biocomputational studies on protein structures

    Författare :Erik Nordling; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Biology in the post-genomic era produces large amount of data. This, in combination with the need for efficient algorithms to find genes in the genomic material, has brought a renaissance into the field of computational biology. LÄS MER

  7. 5. Molecular simulations of G protein-coupled receptors : A journey into structure-based ligand design and receptor function

    Författare :Pierre Matricon; Jens Carlsson; Bjørn Olav Brandsdal; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; G Protein-Coupled Receptor; Molecular Dynamics Simulations; Free Energy Perturbation; Ligand Binding; Fragment-Based Lead Discovery; Molecular Docking Screens; Homology Modeling; GPCR Activation Mechanism; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : The superfamily of G protein-coupled receptors (GPCRs) contains a large number of important drug targets. These cell surface receptors recognize extracellular signaling molecules, which stimulates intracellular pathways that play major roles in human physiology. LÄS MER