Sökning: "primary sclerosing cholangitis"

Visar resultat 1 - 5 av 26 avhandlingar innehållade orden primary sclerosing cholangitis.

1. 1. Cholangiocarcinoma in primary sclerosing cholangitis

   Författare :Annika Bergquist; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Primary sclerosing cholangitis; pancreatic carcinoma; cholangiocarcinoma; ulcerative colitis; biliary dysplasia; apoptosis; Ki-67; p53; bcl-2.;

   Sammanfattning : Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown causes closely associated with ulcerative colitis. PSC is a progressive disease leading to liver failure and need for liver transplantation. Cholangiocarcinoma (CC) occurs in 10-20% of patients with PSC. LÄS MER

3. 2. Autoantigens in Inflammatory Bowel Disease and Primary Sclerosing Cholangitis

   Författare :Brita Ardesjö; Olov Ekwall; Olle Kämpe; Fredrik Rorsman; Eric Gershwin; Uppsala universitet; []
   Nyckelord :Molecular medicine; inflammatory bowel disease; primary sclerosing cholangitis; autoimmunity; autoantigen; goblet cell; Molekylärmedicin;

   Sammanfattning : Inflammatory bowel disease (IBD) comprises diseases that are characterized by chronic or relapsing inflammation of the gastrointestinal tract. Primary sclerosing cholangitis (PSC) is an extraintestinal manifestation in IBD. LÄS MER

4. 3. Studies of ulcerative colitis with concomitant primary sclerosing cholangitis : Beyond the clinical phenotype

   Författare :Johan Vessby; Marie Carlson; Maria Lampinen; Mikael Åberg; Fredrik Rorsman; Björn Lindkvist; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IBD; PSC; ulcerative colitis; PSC-UC; immunology; eosinophils; T cells; tissue factor; proteomics; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Inflammatory bowel disease (IBD) is a group of chronically relapsing immune-related disorders, engaging the gastrointestinal tract. Symptoms vary depending on inflammatory phenotype, but may include diarrhoea, bowel pain and weight loss. The two most common entities are Crohn's disease and ulcerative colitis (UC). LÄS MER

5. 4. Gallbladder and pancreatic disease in patients with primary sclerosing cholangitis

   Författare :Karouk Said; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Cholecystitis; gallbladder; ejection fraction; magnetic resonance imaging; pancreatic duct; chronic pancreatitis; thioredoxin; Immunohistochemical staining;

   Sammanfattning : The aims of this study were to assess the occurrence of gallbladder abnormalities and dysfunction, to evaluate clinically useful biomarkers for premalignancy and malignancy in gallbladder epithelium and to assess presence of pancreatic duct changes and early pancreatic abnormalities in patients with primary sclerosing cholangitis (PSC). In paper I and III we investigated presence of gallbladder abnormalities in 286 patients with PSC treated at Karolinska University Hospital, Huddinge, between 1970 and 2005. LÄS MER

7. 5. Biliary strictures in primary sclerosing cholangitis : aspects on inflammation and malignancy

   Författare :Erik von Seth; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Primary sclerosing cholangitis (PSC) is a rare liver disease that is characterized by chronic inflammation of bile ducts with development of fibrosis and strictures. The pathogenic mechanisms involved in this disease are insufficiently understood. LÄS MER