Sökning: "polarity"

Visar resultat 1 - 5 av 218 avhandlingar innehållade ordet polarity.

  1. 1. Regulation of cell polarity and invasion by TGF-β and BMP signaling

    Författare :Mahsa Shahidi Dadras; Aristidis Moustakas; Petra Knaus; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cancer; cancer stem cells; invasion; metastasis; polarity; TGF-β signaling.;

    Sammanfattning : Transforming growth factor β (TGF-β) and bone morphogenetic protein (BMP) signaling pathways are involved in many physiological processes during embryonic and adult life. TGF-β promotes epithelial to mesenchymal transition (EMT). We identified a gene target of TGF-β signaling, encoding the salt-inducible kinase 1 (SIK1). LÄS MER

  3. 2. RhoGTPase Signaling in Cell Polarity and Gene Regulation

    Författare :Ann-Sofi Johansson; Pontus Aspenström; Johan Lennartsson; Christer Larsson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; RhoGTPase; Par6; cell polarity; aPKC; epithelial cell; PDGF; gene regulation; microarray; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : RhoGTPases are proteins working as molecular switches as they bind and hydrolyze GTP. They are in their active conformation when GTP is bound and are then able to interact with their effector proteins, which relay the downstream signaling. When the GTP is hydrolyzed to GDP, the RhoGTPase is inactivated. LÄS MER

  4. 3. Characterization of New Players in Planar Polarity Establishment in Arabidopsis

    Författare :Stefano Pietra; Markus Grebe; Niko Geldner; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; SABRE; planar polarity; CLASP; cell division orientation; microtubule cytoskeleton; actin; AIP1; patterning; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Sammanfattning : Coordinated polarity and differentiation of cells in the plane of a tissue layer are essential to the development of multicellular organisms. Arabidopsis thaliana root hairs and trichomes provide model systems to study the pathways that control planar polarity and cell fate specification in plants. LÄS MER

  5. 4. Using Molecular Dynamics Simulations to Explore Critical Property Relationships in Polymer Electrolytes : Polarity, Coordination, Ionic transport, Ion-pairing, and Ion-ion Correlations

    Författare :Harish Gudla; Daniel Brandell; Chao Zhang; Andreas Heuer; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Solid polymer electrolytes; molecular dynamics simulations; solvent polarity; ion-pairing; ion coordination; ion transport mechanisms; Kemi med inriktning mot materialkemi; Chemistry with specialization in Materials Chemistry; Kemi med inriktning mot materialkemi; Chemistry with specialization in Materials Chemistry;

    Sammanfattning : While ion transport in solid polymer electrolytes (SPEs) has been explored for decades, there still remains controversies about its fundamental properties, often correlated with gaps between experimental and computational studies. Using molecular dynamics simulations to understand the complex transport mechanisms and also to fill these gaps is the main goal of this thesis. LÄS MER

  7. 5. Parameters affecting the functionality of additives in lubricated contacts : effect of base oil polarity

    Författare :Aldara Naveira Suarez; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Maskinelement; Machine Elements;

    Sammanfattning : Traditionally rolling contact fatigue observed in bearing field applications was subsurface initiated. However, despite the improvement of steel properties, some factors such as downsizing in bearing design, extreme loading of the bearings as well as demanding application conditions (start up-stop cycles) have led to an increase on the cases of surface damage related to surface initiated fatigue, that comes basically from surface distress. LÄS MER