Sökning: "plasma protease inhibitors"

Visar resultat 1 - 5 av 25 avhandlingar innehållade orden plasma protease inhibitors.

  1. 1. Secretory Leukocyte Protease Inhibitor (SLPI) in the gastrointestinal tract in man

    Författare :Max Nyström; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; elastase inhibitors; human leukocyt proteases; Plasma protease inhibitors; NGAL; Ulcerative colitis; Antileukoprotease; IBD; traumatologi; ortopedi; traumatology; orthopaedics; Immunology; serology; transplantation; Immunologi; serologi; Kirurgi;

    Sammanfattning : Secretory leukocyte protease inhibitor is a 11.7 kDa acid stable serine protease inhibitor. SLPI has been shown to be the dominant protease inhibitor in bronchial secretions and has been used in treatment of pulmonary emphysema. LÄS MER

  3. 2. Serine protease inhibitors in the upper and lower airways

    Författare :Camilla Hollander; Enheten för kroniska inflammatoriska och degenerativa sjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; auditive system and speech; Neutrophils; audiology; Otorhinolaryngology; Medicin människa och djur ; AAT; Medicine human and vertebrates ; SLPI; cytokines chemokines; anti-proteases; audiologi; hörsel- och talorganen; Airway inflammation; Otorinolaryngologi;

    Sammanfattning : Proteases and their inhibitors are implicated in the physiology and pathology of the airways. Protease inhibitors include those produced locally, such as secretory leukocyte protease inhibitor (SLPI), and those produced mainly by the liver that can reach the airways via passive diffusion, such as alpha1-antitrypsin (AAT). LÄS MER

  4. 3. Human Glandular Kallikrein 2

    Författare :Janita Lövgren; Malmö Klinisk kemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; seminal plasma; semenogelin; PCI; serpin; zinc; cancer; prostate; PSA; hK2; serine protease; kallikrein; Clinical chemistry; Klinisk kemi;

    Sammanfattning : Human glandular kallikrein 2 (hK2) is a serine protease, which is predominantly expressed by the prostate gland and found in seminal plasma at mean levels of 6 mg/ml. It has 79% amino acid sequence identity with prostate-specific antigen (PSA or hK3). LÄS MER

  5. 4. Experimental and Clinical Studies of SLPI, with Special Reference to IgE-Mediated Allergic Reactions

    Författare :Ulla Westin; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; in situ hybridisation; immunohistochemistry; allergic rhinitis; atopic subjects; IgE-mediated histamine release; mast cell proteases; plasma protease inhibitors; SLPI; human leukocyte proteases; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : In this study we demonstrated the production of SLPI (Secretory Leukocyte Protease Inhibitor) in serous glands in the nasal mucosa. We have shown that the pattern of the expression of mRNA corresponds to the encoded protein. The encoded protein was detected by immunohistochemical methods and mRNA was discovered by in situ hybridisation. LÄS MER

  7. 5. Alpha 1-antitrypsin: A Role in Cancer Progression

    Författare :Inga Zelvyté; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; onkologi; Cytologi; cancerology; oncology; Cytology; invasion; neutrophils; cancer cell; Alpha1- antitrypsin; proteinase inhibitors;

    Sammanfattning : Alpha1-antitrypsin (AAT), a circulating single-chain glycoprotein is the most abundant serine proteinase inhibitor in human plasma. AAT is an acute phase protein, its levels increase rapidly to concentrations exceeding 50mM in response to inflammation, infection and malignant diseases. LÄS MER