Sökning: "piperazine"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet piperazine.

1. 1. Reaction Between Grignard reagents and Heterocyclic N-oxides : Synthesis of Substituted Pyridines, Piperidines and Piperazines

   Författare :Hans Andersson; Fredrik Almqvist; Hans Adolfsson; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Grignard reagents; pyridine N-oxide; pyrazine N-oxide; dienal-oxime; pyridine; ortho- metalation; piperidine; piperazine; asymmetric; Organic synthesis; Organisk syntes; organisk kemi; Organic Chemistry;

   Sammanfattning : This thesis describes the development of new synthetic methodologies for preparation of bioactive interesting compounds, e.g. substituted pyridines, piperidines or piparazines. Thesecompounds are synthesized from commercially available, cheap and easily prepared reagents, videlicet the reaction between Grignard reagents and heterocyclic N-oxides. LÄS MER

3. 2. In vitro cellular models for neurotoxicity studies : neurons derived from P19 cells

   Författare :Dina Popova; Jacobsson Stig O.P.; Anna Forsby; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurotoxicity; Neuronal cell culture; P19 cells; SH-SY5Y cells; βIII-tubulin; Methylmercury; Okadaic acid; Acrylamide; MDMA; Piperazine-derived designer drugs.;

   Sammanfattning : Humans are exposed to a variety of chemicals including environmental pollutants, cosmetics, food preservatives and drugs. Some of these substances might be harmful to the human body. LÄS MER

4. 3. Synthesis of a targeted library and thrombin inhibitors using organometallic chemistry

   Författare :Fredrik Thorstensson; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : The use of organometallic chemistry in the pursuit of novel scaffolds is outline d. A 4-phenyl- 2-carboxy-piperazine targeted combinatorial chemistry library has been synthesized aimed at the early lead discovery phase. LÄS MER

5. 4. Energy Efficient Processes for the Production of Gaseous Biofuels - Reforming and Gas Upgrading

   Författare :Helena Svensson; Avdelningen för kemiteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biofuels; Reverse-flow reforming; Gas upgrading; Amine absorption;

   Sammanfattning : Replacing fossil fuels with biofuels is one way of reducing the emission of greenhouse gases into the atmosphere, thus decreasing our impact on the global climate. For this to be a viable option, several production routes are needed, as no single option can fully replace fossil fuels. LÄS MER

7. 5. Amphiphilic Molecules in Aqueous Solution

   Författare :Gerd Persson; Göran Lindblom; Håkan Edlund; Björn Lindman; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; liquid crystal; phase diagrams; counterions; alkylpyridinium octanesulfonates; 1-monooleoyl-rac-glycerol; n-octyl-β-D-glucoside; cubic phases; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; Physical Chemistry; fysikalisk kemi;

   Sammanfattning : The aim of this thesis was to investigate amphiphilic molecules in aqueous solution. The work was divided into two parts. In the first part the effects of different counterions on phase behavior was investigated, while the second part concerns the 1-monooleoyl-rac-glycerol (MO)/n-octyl-β-D-glucoside (OG)/2H2O-system. LÄS MER