Sökning: "pharmaceutical mixtures"

Visar resultat 1 - 5 av 33 avhandlingar innehållade orden pharmaceutical mixtures.

  1. 1. Pharmaceutical Nanocomposites : Structure–Mobility–Functionality Relationships in the Amorphous State

    Författare :Joel Hellrup; Denny Mahlin; Göran Alderborn; László Fábián; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; amorphous; pharmaceutical composites; solid state; structure; molecular mobility; spray-drying; freeze-drying; moisture sorption; physical stability; compression; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Amorphous materials are found in pharmaceutical formulations both as excipients and active ingredients. Indeed, these formulations are becoming an essential strategy for incorporating drugs into well-performing solid dosage forms. LÄS MER

  3. 2. Understanding Adhesive Mixtures for Inhalation : Particle Dynamics Modelling and Segregation Experiments

    Författare :Sohan Sarangi; Göran Frenning; Göran Alderborn; Kyrre Thalberg; Johannes Khinast; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inhalation; adhesive mixtures; dry powder inhaler; discrete element method; segregation; stability; modeling; Galenisk farmaci; Pharmaceutics; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Pulmonary route has been used as a source of drug delivery to lungs for centuries. Drugformulation decides the type of inhaler devices such as pressurized metered-dose inhalers(pMDIs), nebulizers and dry powder inhalers (DPIs). LÄS MER

  4. 3. Pharmaceutical binders and their function in directly compressed tablets : Mechanistic studies on the effect of dry binders on mechanical strength, pore structure and disintegration of tablets

    Författare :Sofia Mattsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; Compaction; tablet; binder; pore structure; disintegration; FARMACI; PHARMACY; FARMACI; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Sammanfattning : In this thesis, the strength-enhancing mechanisms of dry binders in direct compression were studied. The systems investigated were binary mixtures containing various compounds and binders. Among the binders used were a series of different molecular weights of polyethylene glycol. LÄS MER

  5. 4. Powder mechanics and dispersion properties of adhesive mixtures for dry powder inhalers : Conceptualized as a blend state model

    Författare :Jonas Rudén; Göran Alderborn; Göran Frenning; Tobias Bramer; Kyrre Thalberg; Regina Scherliess; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inhalation; Dry Powder Inhaler; adhesive mixture; aerosols; powder mechanics; dispersibility; aerosolization; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Inhaled medicines is a therapy that dates back several thousands of years. Nowadays, using various types of inhaler devices to deliver active pharmaceutical ingredients (APIs) to treat respiratory diseases has become common practice. LÄS MER

  7. 5. Compression analysis as a tool for technical characterization and classification of pharmaceutical powders

    Författare :Josefina Nordström; Göran Alderborn; Maria Strömme; Katharina Picker-Freyer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; compaction; compression; granules; Kawakita; mechanical properties; particles; PAT; pharmaceutical powders; tablets; Pharmaceutics; Galenisk farmaci;

    Sammanfattning : There are today strong incentives for an increased understanding of material properties and manufacturing processes to facilitate the development of new technologies in the pharmaceutical industry. The purpose of this thesis was to suggest methods requiring a low sample amount for characterization of technical properties of powders. LÄS MER