Sökning: "phagosome"
Visar resultat 1 - 5 av 22 avhandlingar innehållade ordet phagosome.
1. Phagocytosis by neutrophils - studies on phagosome dynamics and membrane traffic modulation by Streptococcus pyogenes
Sammanfattning : Neutrophils are our most numerous and deadly white blood cells and without them we would succumb quickly to infections by pathogens. The main mechanism that the neutrophils employ for our protection is phagocytosis, where they eat and enclose their target inside a membrane-bound organelle, the phagosome. LÄS MER
2. Mechanisms of the intracellular survival of Francisella tularensis
Sammanfattning : Francisella tularensis is a gram-negative, highly virulent, intracellular bacterium which causes the zoonotic disease tularemia. The subspecies tularensis and holarctica are clinically important, and the former is the more virulent. The intracellular lifestyle of F. LÄS MER
3. Reactive oxygen and nitrogen in host defence against Francisella tularensis
Sammanfattning : Francisella tularensis, the causative agent of tularemia, is a potent human and animal pathogen. Initially upon infection of the host, intramacrophage proliferation of F. tularensis occurs but after activation of the acquired host immunity, the phagocytes become activated to kill the bacterium. In my thesis, I focused on mechanisms utilized by F. LÄS MER
4. Characterization of the attenuated Francisella tularensis strain FSC043 : with special focus on the gene pdpC
Sammanfattning : Francisella tularensis is a highly infective, intracellular bacterium. It is capable of infecting a wide range of mammals and causes the disease tularemia in humans. As a result of its high infectivity there have been a lot of efforts made to create a generally available vaccine against this pathogen. LÄS MER
5. Regulation of phagocytosis and phagolysosome fusion in human leukocytes
Sammanfattning : Professional phagocytes such as neutrophil granulocytes and macrophages are an esential part of the innate immune system. The neutrophils form the first line of defence against invading microorganisms and are important for rapid killing of the intruders. LÄS MER