Sökning: "phagocytes"

Visar resultat 1 - 5 av 72 avhandlingar innehållade ordet phagocytes.

  1. 1. Human mononuclear phagocytes : Production of reactive oxygen species generated by the NADPH oxidase

    Författare :Agneta Johansson; Roger Sundler; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Human professional phagocytes constitute the first line of defence against invading microorganisms. With a membrane-bound enzyme system, the NADPH oxidase, these cells generate bactericidal metabolites. Activation of NADPH oxidase results in a generation of reactive oxygen species, e.g. LÄS MER

  3. 2. Reactive oxygen species as signalling molecules in immunity

    Författare :Åsa Betten; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reactive oxygen species; NK cells; phagocytes; serotonin; histamine; myeloperoxidase;

    Sammanfattning : Cytotoxic lymphocytes such as natural killer (NK) cells and subsets of T cells are key components of the host defense against malignancy and infection. Earlier studies have demonstrated that NK cells and several phenotypes of T cells become dysfunctional and apoptotic after exposure to autologous monocyte/macrophages and other phagocytes. LÄS MER

  4. 3. Innate and acquired immunity to herpes simplex virus type 2 glycoprotein G in humans

    Författare :Lars Bellner; Göteborgs universitet; []
    Nyckelord :herpes simplex virus type 2; glycoprotein G-2; T-cell proliferation; Th1 cytokines; phagocytes; NK cells; reactive oxygen species; formyl peptide receptors;

    Sammanfattning : Herpes simplex virus type 2 (HSV-2) is a sexually transmitted pathogen that infects the human genital tract mucosa and is the most common cause of genital ulcer disease in humans. The infection exhibits a broad clinical spectrum, ranging from severe recurrent episodes of genital herpes to being completely asymptomatic. LÄS MER

  5. 4. Oxidant-induced cell death in lymphocytes: mechanisms of induction and resistance

    Författare :Fredrik Bergh Thorén; Göteborgs universitet; []
    Nyckelord :reactive oxygen species; cell death; apoptosis; poly ADP-ribose polymerase-1; apoptosis-inducing factor; natural killer cells; phagocytes; dendritic cells;

    Sammanfattning : Reactive oxygen species (oxidants, oxygen radicals) produced by the phagocytic NADPH oxidase have pivotal roles in immunity. Patients lacking a functional NADPH oxidase suffer from chronic granulomatous disease, which is characterized by recurring bacterial infections and thus manifesting the importance of reactive oxygen species in host defense against bacteria. LÄS MER

  7. 5. Cell death and clearance - studies of human neutrophils from blood and tissue

    Författare :Karin Christenson; Göteborgs universitet; []
    Nyckelord :neutrophils; apoptosis; transmigration; phagocytes;

    Sammanfattning : Neutrophils are phagocytic cells that typically migrate from circulation to tissues in order to combat microbial invasion. The journey from blood to tissue involves mobilization of intracellular organelles which results in modifications of surface markers (e.g. LÄS MER