Sökning: "per-olof syren"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden per-olof syren.
1. On electrostatic effects, minimal motion and other catalytic strategies used by enzymes
Sammanfattning : Enzymes are powerful biocatalysts that provide rate accelerations of up to 1019 fold compared to the corresponding uncatalyzed reaction in solution. The origin of the remarkable performance displayed by enzymes has fascinated and puzzled researchers for over a hundred years. LÄS MER
2. Engineering enzymes towards biotherapeutic applications using ancestral sequence reconstruction
Sammanfattning : Enzymes are versatile biocatalysts that fulfill essential functions in all forms of life and, therefore, play an important role in health and disease. One specific application of enzymes in life science is their use as biopharmaceuticals, which typically benefits from high catalytic activity and stability. LÄS MER
3. In silico protein design for the enhancement of protein stability and function
Sammanfattning : Enzymes are natures catalysts that increase the rate of a chemical reaction. The increased rate of a reaction is required to be able to sustain life. Despite the huge impact of enzymes, they are not perfect catalysts. LÄS MER
4. On Catalytic Mechanisms for Rational Enzyme Design Strategies
Sammanfattning : Enzymes enable life by promoting chemical reactions that govern the metabolism of all living organisms. As green catalysts, they have been extensively used in industry. However, to reach their full potential, engineering is often required, which can benefit from a detailed understanding of the underlying reaction mechanism. LÄS MER
5. Sequence- and structure guided engineering of proteins and enzymes for biotechnology and health applications
Sammanfattning : Proteins are highly diverse and sophisticated biomolecules that represent a cornerstone of biological structure and function and have been exploited in man-made applications for thousands of years. Those proteins that facilitate chemical reactions at physiologically relevant time-scales are referred to as enzymes. LÄS MER