Sökning: "peptide fragmentation"
Visar resultat 1 - 5 av 29 avhandlingar innehållade orden peptide fragmentation.
1. Amphiphilic Peptide Interactions with Complex Biological Membranes : Effect of peptide properties on antimicrobial and anti-inflammatory effects
Sammanfattning : With increasing problem of resistance development in bacteria against conventional antibiotics, as well as problems associated with diseases either triggered or enhanced by infection, there is an urgent need to identify new types of effective therapeutics for the treatment of infectious diseases and its consequences. Antimicrobial and anti-inflammatory peptides have attracted considerable interest as potential new antibiotics in this context. LÄS MER
2. New Proteomics Methods and Fundamental Aspects of Peptide Fragmentation
Sammanfattning : The combination of collision-activated dissociation, (CAD) and electron capture dissociation, (ECD) yielded a 125% increase in protein identification. The S-score was developed for measuring the information content in MS/MS spectra. This measure made it possible to single out good quality spectra that were not identified by a search engine. LÄS MER
3. Improved Neuropeptide Identification : Bioinformatics and Mass Spectrometry
Sammanfattning : Bioinformatic methods were developed for improved identification of endogenous peptides using mass spectrometry. As a framework for these methods, a database for endogenous peptides, SwePep, was created. It was designed for storing information about endogenous peptides including tandem mass spectra. LÄS MER
4. Substance P and calcitonin gene-related peptide in sensory neurons : their fragmentation and substance P precursor forms
Sammanfattning : .... LÄS MER
5. Method and technique development in peptide and protein mass Spectrometry
Sammanfattning : Mechanistic studies and applicability of several methods and techniques for studying peptides and proteins with mass spectrometry are presented. A model for the protein molecular ion formation in explosive matrix-assisted plasma desorption mass spectrometry is proposed, involving a contribution from the chemical energy release during conversion of the explosive, an enhanced protonation through collisions with products from the explosive decay, and electron scavenging by other products. LÄS MER