Sökning: "pedigree"

Visar resultat 1 - 5 av 57 avhandlingar innehållade ordet pedigree.

  1. 1. Detecting Deletions by Analysis of Genetic Markers in Pedigrees

    Författare :Anna Johansson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytogenetics; Genetik; Genetics; Biologi; genetic marker; pedigree; Protein S deficiency; Biology; PROS1; deletion; null allele; cytogenetik;

    Sammanfattning : A deletion is defined as a missing piece of a chromosome, ranging in size from as small as a single base pair to as much as an entire arm of a chromosome. Deletions can cause diseases, but may also have a neutral effect in the genome. LÄS MER

  3. 2. Dynamics of inbreeding and genetic rescue in a small population

    Författare :Malin Hasselgren; Karin Norén; Carles Vilà; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; inbreeding; inbreeding depression; genetic rescue; fitness; genomics; conservation genetics; mutational load; arctic fox; pedigree; gene flow; zoologisk ekologi; Animal Ecology;

    Sammanfattning : Isolation at small population size can reduce individual fitness and impede population growth caused by inbreeding and genetic drift (i.e. inbreeding depression). Inbreeding depression can however be circumvented by gene flow from unrelated individuals through masking of recessive deleterious alleles and contribute to population persistence (i. LÄS MER

  4. 3. Gene Mapping in Ficedula Flycatchers

    Författare :Niclas Backström; Hans Ellegren; Juha Merilä; Uppsala universitet; []
    Nyckelord :collared flycatcher; SNP; linkage disequilibrium; genetic map; pedigree;

    Sammanfattning : In order to get full understanding of how evolution proceeds in natural settings it is necessary to reveal the genetic basis of the phenotypic traits that play a role for individual fitness in different environments. There are a few possible approaches, most of which stem from traditional mapping efforts in domestic animals and other model species. LÄS MER

  5. 4. Vägen till vinnarcirkeln. Travhästen och dess människor mellan sport och spel

    Författare :Sara Berglund; Avdelningen för etnologi; []
    Nyckelord :HUMANIORA; HUMANITIES; harness racing; trotting; horse; gambling; competition; sport; training; breeding; pedigree; sportification; totalizator; quantification; organisation; cloning; insemination; etnologi; Kulturantropologi; Cultural anthropology; naming; ethnology; kinship;

    Sammanfattning : The way we understand and treat our horses, like the purpose for which they are bred, is culturally conditioned. The transition between differing social formations involves not only new life circumstances for people and animals, but also changed social modes of relating between them. LÄS MER

  7. 5. Epidemiological and genetic studies of muliple sclerosis with focus on the Swedish county of Värmland

    Författare :Margarita Callander; Anders Svenningsson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inborn genetic diseases; Genetic predisposition to disease; Genetic predisposition to disease; Cluster analysis; Muliple sclerosis; Pedigree; Medical genetics; Medicinsk genetik;

    Sammanfattning : The aim of this study was to perform detailed investigations of a presumed high-risk area, namely the county of Värmland, to see if previous results from our group indicating a high frequency of multiple sclerosis (MS) could be confirmed. We soon identified an aggregation of MS cases in the parish of Lysvik located in the north of Värmland and initiated epidemiological and genetical analyses of the population. LÄS MER