Sökning: "parapertussis"

Hittade 2 avhandlingar innehållade ordet parapertussis.

1. 1. Aspects of pertussis, pertussis vaccination and adverse events associated with aluminum adsorbed vaccines

   Författare :Elisabet Bergfors; Göteborgs universitet; []
   Nyckelord :Pertussis; parapertussis; pertussis toxoid; vaccine; vaccination; vaccine trial; adjuvant; aluminium; adsorbed vaccines; adverse event; pruritic nodules; itching nodules; granuloma; sensitisation; hypersensitivity; contact allergy;

   Sammanfattning : The thesis originates in a clinical study of one of the new acellular pertussis vaccines performed in Göteborg in the 1990s. The monocomponent vaccine, pertussis toxoid adsorbed to aluminium hydroxide, had previously been shown to have an efficacy of 71%. LÄS MER

3. 2. Laboratory diagnosis of Bordetella infection : DNA hybridization and PCR validated against serology and culture in a phase 3 vaccine efficacy trial

   Författare :Elisabet Reizenstein; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The present study has focused on developing and validating assays alternative to culture for detection of Bordetella pertussis. The sensitivity of culture is comparatively low when compared to serology, varying from 30% to 80%. An attempt to increase this sensitivity was made by development of assays detecting the DNA of the bacteria. LÄS MER