Sökning: "pancreatic lipase"

Visar resultat 11 - 15 av 20 avhandlingar innehållade orden pancreatic lipase.

  1. 11. Hormone-Sensitive Lipase - New roles in adipose tissue biology

    Författare :Kristoffer Ström; Molekylär endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; retinoid; adipogenesis; adipocyte determination; HSL; WAT;

    Sammanfattning : Obesity is defined as abnormal or excessive fat accumulation that may impair health, and increased knowledge about the enzymes controlling lipid metabolism is of great importance in order to combat this disease. Hormone-sensitive lipase (HSL) is a key enzyme in the mobilization of fatty acids from acylglycerols in adipocytes, but also plays important roles in other cell types. LÄS MER

  3. 12. Glucose and lipid metabolism in insulin resistance : an experimental study in fat cells

    Författare :Jonas Burén; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; adipocyte; insulin resistance; type 2 diabetes; insulin signalling; glucose uptake; insulin; glucose; dexamethasone; insulin receptor substrate; protein kinase B; GLUT4; lipoprotein lipase; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden; medicin; Medicine;

    Sammanfattning : Type 2 diabetes is usually caused by a combination of pancreatic β-cell failure and insulin resistance in target tissues like liver, muscle and fat. Insulin resistance is characterised by an impaired effect of insulin to reduce hepatic glucose production and to promote glucose uptake in peripheral tissues. LÄS MER

  4. 13. Lipid metabolism in the pancreatic beta-cell. Implications for insulin secretion

    Författare :Malin Fex; Celiaki och diabetes; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; sekretion; diabetologi; Endocrinology; secreting systems; Lipid metabolism; Insulin secretion; Beta-cells;

    Sammanfattning : We have investigated the role of lipid metabolism with regard to beta-cell function and insulin secretion. Lipids are known to play a crucial functional role in the pancreatic beta-cell, where they are essential for adequate hormone release, but may also exert a long-term toxic effect, leading to beta-cell dysfunction. LÄS MER

  5. 14. Lipases and phenolic aggregates : Characterization, inhibition and interaction

    Författare :Atma-Sol Bustos; Avdelningen för livsmedel och läkemedel; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : In recent decades, obesity has gone from being a problem of first world countries to a global one. It is considered one of the main risk factors for many serious medical conditions. LÄS MER

  7. 15. Enterostatin in the Gastrointestinal Tract - Production and Possible Mechanism of Action

    Författare :Maria Sörhede Winzell; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; insulin secretion; neuropeptide; lipolysis; appetite; Colipase; fat intake; Fysiologi;

    Sammanfattning : The presence of procolipase and enterostatin in the rat gastrointestinal tract has been investigated. Procolipase was identified, using in situ hybridization and immunohistochemistry, in exocrine cells of the pancreas as well as in chief cells of the fundus region of the stomach. LÄS MER