Sökning: "pancreas development"

Visar resultat 21 - 25 av 95 avhandlingar innehållade orden pancreas development.

1. 21. Studies of Enterovirus Infection and Induction of Innate Immunity in Human Pancreatic Cells

   Författare :Mahesh Anagandula; Magnus Essand; Didier Hober; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 Diabetes; Enterovirus; Innate Immunity; Pancreas;

   Sammanfattning : Several epidemiological and clinical studies have indicated a possible role of Enterovirus (EV) infection in type 1 diabetes (T1D) development. However, the exact casual mechanism of these viruses in T1D development is not known. LÄS MER

3. 22. In vivo and in vitro approaches to induce beta cells from stem and progenitor cells

   Författare :Lars Selander; Helena Edlund; Yuval Dor; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreas; stem cell; progenitor; beta cell; in vitro; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; molecular medicine medical sciences ; molekylär medicin medicinska vetenskaper ;

   Sammanfattning : Diabetes or diabetes mellitus which is the correct medical term is a medical condition were the affected person lack the ability to regulate his or her blood glucose levels. This inability is directly due to the fact that the insulin producing cells, residing in the pancreas, can’t meet the body’s demand for insulin. LÄS MER

4. 23. On macrophage contributions to tissue homeostasis : New insights on pancreas development and healing of ischemic injury

   Författare :Carmen Herrera Hidalgo; Mia Phillipson; Andrés Hidalgo; Uppsala universitet; []
   Nyckelord :macrophages; islets of Langerhans; β cell function; postnatal β cell maturation; hindlimb ischemia; blood flow regulation; mural cells; vessel pruning; diabetes mellitus; ischemic diseases;

   Sammanfattning : Besides providing host defence against innumerable threats, macrophages display additional key functions for preservation of tissue homeostasis. This thesis includes four studies that explore novel macrophage functions in both the development of islets of Langerhans and healing of ischemic injury in mice. LÄS MER

5. 24. Developmental and methodological aspects of intestinal and pancreatic function in pigs and rats

   Författare :Klas Rådberg; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; macromolecule; endocytosis; FITC-dextran; secretion; mucosa; CCK; pancreas; disaccharidase; intestinal permeability; lectin; morphometry; Animal physiology; Djurfysiologi;

   Sammanfattning : The gastrointestinal tract has two opposing functions; to effectively absorb nutrients and to act as a safety barrier against hazardous substances in the environment. After birth these functions develops gradually. LÄS MER

7. 25. Human Embryonic Stem Cells - Constitutive Gene Expression and Differentiation Towards Definitive Endoderm and Posterior Foregut Endoderm

   Författare :Karin Norrman; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human embryonic stem cells; diabetes; pancreas; definitive endoderm; foregut endoderm; pancreatic endoderm; constitutive promoter; ACTB; EF1alpha; CMV; PGK; UbC;

   Sammanfattning : Abstract More than 300 million people are suffering from diabetes worldwide and the numbers of diabetic patients are increasing. Today´s treatments mainly rely on daily insulin injections. This help people to control blood glucose levels but still many patients suffer from the many complications associated with diabetes. LÄS MER