Sökning: "pancreas development"

Visar resultat 1 - 5 av 79 avhandlingar innehållade orden pancreas development.

  1. 1. Imaging the pancreas new aspects on lobular development and adult constitution

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Andreas Hörnblad; Umeå universitet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; ß-cell mass; tertiary lymphoid organs; biomedical imaging; optical projection tomography; morphogenesis; pancreas development; gastric lobe; spleen development.; medicinsk genetik; Medical Genetics; medicinsk utvecklings- och neurobiologi; Developmental Neurosciences; molekylär medicin genetik och patologi ; Molecular Medicine;

    Sammanfattning : The mouse pancreas is a mixed exocrine and endocrine glandconsisting of three lobular compartments: the splenic, duodenal and gastric lobes. During embryogenesis, the pancreas forms from two progenitor populations located on the dorsal and ventral side of the primitive gut tube. LÄS MER

  2. 2. The MEN 1 Pancreas Tumor Development and Haploinsufficiency

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Margareta Halin Lejonklou; Uppsala universitet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEN 1; PNET; tumor development; haploinsufficiency; survivin; Endocrinology and Diabetology; Endokrinologi och Diabetologi;

    Sammanfattning : Multiple Endocrine Neoplasia Type I Syndrome (MEN 1) is a monogenic autosomal dominantly inherited cancer syndrome caused by a heterozygous loss of the MEN1 gene, predisposing for endocrine cell proliferation and tumor formation. MEN 1 carriers classically develop tumors in endocrine organs; the parathyroids, the endocrine pancreas, and the pituitary. LÄS MER

  3. 3. Spleno-pancreatic development assessed by 3D molecular imaging

    Detta är en avhandling från Umeå : Umeå centrum för molekylär medicin (UCMM)

    Författare :Amir Asayesh; Umeå universitet.; [2007]
    Nyckelord :Cell biology; Spleen; Pancreas; Imaging; Development; Cellbiologi; miljömedicinsk utvecklingsbiologi; Developmental Biology;

    Sammanfattning : The development of different organs and tissues along the gastrointestinal tract, including the pancreas, depends on signalling between the endoderm and the adjacent mesenchyme. The Nkx gene Bapx1 is involved in spatial control of organ-positioning in the spleno-pancreatic region, and deficiency in this gene results in unacceptable proximity of the splenic mesenchyme to the pancreas. LÄS MER

  4. 4. Pancreas Transplantation: Development of Successful Preclinical Models

    Detta är en avhandling från Surgery Research Unit

    Författare :Wayne John Hawthorne; Lunds universitet.; Lund University.; [1997]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute rejection; simultaneous pancreas and kidney transplant; portal venous drainage; systemic venous drainage; pancreaticoduodenal transplant; segmental pancreas transplant; duct-occlusion; autograft; Pancreas transplantation; allograft; hyperacute rejection; glucose metabolism.; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : Pancreas transplantation is today a technically successful procedure and provides an alternative to insulin injections for the treatment of Type I diabetes mellitus. This thesis was undertaken while pancreas transplantation was developing and while several fundamental questions were being asked about both endocrine and exocrine drainage of the transplanted pancreas as well as how best to diagnose and prevent rejection. LÄS MER

  5. 5. Optical projection tomography based 3D-spatial and quantitative assessments of the diabetic pancreas

    Detta är en avhandling från Umeå : Umeå centrum för molekylär medicin (UCMM)

    Författare :Tomas Alanentalo; Umeå universitet.; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nkx; development; optical projection tomography; 3D visualisation; pancreas; beta-cell mass; insulitis; diabetes; NATURAL SCIENCES Biology Cell and molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi;

    Sammanfattning : The gastrointestinal tract comprises a number of digestive organs including the stomach and pancreas. The stomach is involved in the digestion and short term storage of food while the pancreas is a mixed endocrine and exocrine gland which provides the body with hormones and enzymes essential for nutritional utilisation. LÄS MER