Sökning: "open reading frames"

Visar resultat 1 - 5 av 44 avhandlingar innehållade orden open reading frames.

  1. 1. Functional studies of E. coli ribosomes and characterization of mini open reading frames

    Författare :Vildan Dincbas; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : In this thesis, problems concerning the elongation, termination and recycling steps of prokaryotic translation have been addressed.An explanation is given for growth inhibition due to minigene expression.Minigene transcripts containing very short open reading frames inhibit proteinsynthesis in E. LÄS MER

  2. 2. Nora virus as a model to study persistent infection in Drosophila melanogaster

    Författare :Mazen Habayeb; Dan Hultmark; Joachim De Miranda; Molecular Biology; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nora virus; Drosophial; persistence; transmission; RNAi; capsid proteins; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar; molekylärbiologi; Molecular Biology;

    Sammanfattning : Drosophila melanogaster has been widely used as a model organism to study the immune responses against bacteria, fungi, parasites and viruses. Here, I present a D. melanogaster virus as a model to study persistent virus infections. I have discovered and characterized the Nora virus, a small picorna-like RNA virus able to persistently infect D. LÄS MER

  3. 3. The cholecystokinin receptor family : molecular cloning and pharmacological characterization

    Författare :Isabelle Nilsson; Dan Larhammar; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Cholecystokinin (CCK) and gastrin are hormones/neurotransmittors of the gastrointestinal tract and central nervous system. The receptors for gastrin and CCK are members of the G protein-coupled receptor family. The aim of this study was to clone and pharmacologically characterize vertebrate and invertebrate CCK receptors and splice variants. LÄS MER

  4. 4. Sesquiterpene synthases in Artemisia annua: Cloning, Expression, and Characterisation of the Recombinant Enzymes

    Författare :Per Mercke; Kemiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Artemisia annua; Sesquiterpene synthases; artemisinin; Plant biochemistry; Växtbiokemi;

    Sammanfattning : Plants produce a multitude of different compounds that may have biotic effects. Artemisia annua, produces a compound used as a drug against multi-drug-resistant strains of Plasmodium falciparum, the parasite causing malaria. LÄS MER

  5. 5. Genomics of Sorocarpic Amoebae

    Författare :Sanea Sheikh; Sandra L. Baldauf; Matthew W. Brown; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : Sorocarpy is the aggregation of unicellular organisms to form multicellular fruiting bodies (sorocarps). This thesis is about the two best-known groups of sorocarpic amoebae, Dictyostelids and Acrasids.Paper I describes assembly and analysis of a multigene dataset to identify the root of the dictyostelid tree. LÄS MER