Sökning: "olfactory pathway"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden olfactory pathway.

  1. 1. Nasal administration of compounds active in the central nervous system : Exploring the olfactory system

    Författare :Maria Dahlin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; Nasal administration; olfactory pathway; cerebrospinal fluid; autoradiography; FARMACI; PHARMACY; FARMACI; farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Sammanfattning : The nasal administration of drugs offers advantages over administration by intravenous injection. Drugs can be rapidly absorbed through the nasal mucosa, resulting in a rapid onset of action, and also avoiding degradation in the gastrointestinal tract and first-pass metabolism in the liver. LÄS MER

  3. 2. Machine Learning Techniques with Specific Application to the Early Olfactory System

    Författare :Benjamin Auffarth; Anders Lansner; Tony Lindeberg; Tim Pearce; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; feature selection; image features; pattern classification; relevance; redundancy; distributional similarity; divergence measure; genetic algorithms; clustering algorithms; annealing; olfactory coding; olfactory bulb; odorants; glomeruli; property-activity relationship; olfaction; plasticity; axonal guidance; odor category; perception; spatial coding; population coding; memory organization; odor quality; SRA - ICT; SRA - Informations- och kommunikationsteknik;

    Sammanfattning : This thesis deals with machine learning techniques for the extraction of structure and the analysis of the vertebrate olfactory pathway based on related methods. Some of its main contributions are summarized below. LÄS MER

  4. 3. Factors influencing the turnover of olfactory receptor neurons

    Författare :Maja-Lena Deckner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :immunohistochemistry; in situ hybridization; rat; olfactory bulb; olfactory epithelium; axotomy; regeneration; apoptosis; BBB; VEGF; blood vessels; trophic factor; BDNF; trkB; tenascin;

    Sammanfattning : The olfactory system has a striking capacity for neuronal plasticity throughout life and the olfactory epithelium is able to generate both neuronal and non-neuronal cells in the normal adult animal as well as after experimental injury. In contrast to primary sensory neurons, olfactory axons are able to cross the border between the PNS and CNS in the olfactory bulb after transection in the adult animal. LÄS MER

  5. 4. Olfaction in Desert Locusts- Anatomy, Function and Plasticity of the Central Olfactory System

    Författare :Rickard Ignell; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; hist; serotonin; immunocytochemistry; juvenile hormone; development; olfactometer; intracellular recording; evolution; projection neuron; receptor neuron; antennal lobe; aggregation pheromone; neuroethology; olfaction; Desert locust; Schistocerca gregaria; Ecology; Ekologi; Entomology; plant parasitology; Entomologi; växtparasitologi; Environmental chemistry; Miljökemi;

    Sammanfattning : The anatomy, function and plasticity of the primary olfactory centre, the antennal lobe (AL), of the desert locust Schistocerca gregaria was investigated using a number of neuroanatomical and neurophysiological methods. Anatomical characterisation of the AL in a number of orthopteran species made it possible to deduce a model concerning the evolution of microglomeruli. LÄS MER

  7. 5. Assessment of precursor cell proliferation in normal and injured adult mammalian brains

    Författare :Hong Zhu; Göteborgs universitet; []
    Nyckelord :6-OHDA; astrocytes; cell proliferation; neural stem cells; ; neurogenesis; precursor cells; seizure; SVZ-OB pathway;

    Sammanfattning : In the adult mammalian brain, new neurons are generated from neural stem cells (NSCs) which reside in the subventricular zone (SVZ) of the lateral ventricle wall and in the subgranular zone (SGZ) of the dentate gyrus (DG) in the hippocampus. The biology of persistent NSCs in the adult brain is poorly understood. LÄS MER