Sökning: "nucleoid"

Visar resultat 1 - 5 av 14 avhandlingar innehållade ordet nucleoid.

  1. 1. Biological Insights from Single-Particle Tracking in Living Cells

    Författare :Arash Sanamrad; Johan Elf; Måns Ehrenberg; Achillefs Kapanidis; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; single-particle tracking; intracellular diffusion; nucleoid exclusion; transcription-translation coupling; antibiotics; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : Single-particle tracking is a technique that allows for quantitative analysis of the localization and movement of particles. In this technique, trajectories are constructed by determining and connecting the positions of individual particles from consecutive images. LÄS MER

  3. 2. Hypothermia and radiation. Effects on DNA, chromatin and cellular survival

    Författare :Kerstin Elmroth; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cells; temperature; irradiation; dsb; survival; fluorescent nucleoid assay; hypothermia;

    Sammanfattning : The effect of ionising radiation on cells can be modulated by several physico-chemical factors. The aim of this study was to investigate if hypothermic (sub-physiological) temperatures (2°C-28°C) may influence the effect of X-rays on cellular damage in human normal fibroblasts and in a human breast adenocarcinoma cell line, MCF-7. LÄS MER

  4. 3. Molecular mechanisms of mammalian mitochondrial DNA replication and transcription

    Författare :Mina Pellegrini; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Mitochondrion; DNA polymerase gamma; mtSSB; TWINKLE; DNA replication; transcription; mTERF; MTERF3; MTERF2; nucleoid;

    Sammanfattning : Mitochondria are cytoplasmic organelles in eukaryotic cells, mainly devoted to the synthesis of ATP, through the Oxydative Phospshorylation System (OXPHOS). The organelle has its own genome, the mitochondrial DNA (mtDNA) that encodes for all the RNA components of the mitochondrial translation apparatus (two rRNAs and 22 tRNAs) and for 13 subunits of the OXPHOS complexes. LÄS MER

  5. 4. Cell cycle analysis of archaea

    Författare :Andrzej Poplawski; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; mikrobiologi; Microbiology;

    Sammanfattning : In my thesis, the cell cycle analysis of archaea and hyperthermophilic organisms is presented for the first time. Crenarchaea from the genus Sulfolobus were used as a model system. Plow cytometry and light microscopy were applied to investigate the timing and coordination of different cell cycle events. LÄS MER

  7. 5. The role of chromatin in the induction and repair of DNA damage

    Författare :Mats Ljungman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA damage; Chromatin; Kromatin; DNA;

    Sammanfattning : The role of chromatin in the induction and repair of DNA damage has a dual nature.The constituent proteins of chromatin protect the DNA against the induction of DNAdamage, while at the same time they reduce the accessibility of DNA to repair enzymes. LÄS MER