Sökning: "non-covalent interaction"
Visar resultat 1 - 5 av 26 avhandlingar innehållade orden non-covalent interaction.
1. Exploring non-covalent interactions between drug-like molecules and the protein acetylcholinesterase
Sammanfattning : The majority of drugs are small organic molecules, so-called ligands, that influence biochemical processes by interacting with proteins. The understanding of how and why they interact and form complexes is therefore a key component for elucidating the mechanism of action of drugs. LÄS MER
2. Non-covalent Modification of Graphene and MoS2 Synthesis and Characterization of Charged Molecules and Two-Dimensional Materials
Sammanfattning : Graphene is a material of superlatives. It has unique properties, which are explored in various areas of interdisciplinary research. Graphene can improve the properties of other materials or even give them new functions and is therefore a suitable candidate for different sensor applications. LÄS MER
3. Complexes of cell-penetrating peptides with oligonucleotides : Structure, binding and translocation in lipid membranes
Sammanfattning : The fundamental element of life known to man is the gene. The information contained in genes regulates all cellular functions, in health and disease. The ability to selectively alter genes or their transcript intermediates with designed molecular tools, as synthetic oligonucleotides, represents a paradigm shift in human medicine. LÄS MER
4. Identification and Characterization of Peptides and Proteins using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Sammanfattning : Mass spectrometry has in recent years been established as the standard method for protein identification and characterization in proteomics with excellent intrinsic sensitivity and specificity. Fourier transform ion cyclotron resonance is the mass spectrometric technique that provides the highest resolving power and mass accuracy, increasing the amount of information that can be obtained from complex samples. LÄS MER
5. Studies on the Non-covalent Interactions (Stereoelectronics, Stacking and Hydrogen Bonding) in the Self-assembly of DNA and RNA
Sammanfattning : This thesis is based on ten publications (Papers I-X). The phosphodiester backbone makes DNA or RNA to behave as polyelectrolyte, the pentose sugar gives the flexibility, and the aglycones promote the self-assembly or the ligand-binding process. LÄS MER