Sökning: "neuromuscular disease"

Visar resultat 21 - 25 av 64 avhandlingar innehållade orden neuromuscular disease.

  1. 21. Environmental Factors of Importance in Myasthenia Gravis : Emphasis on Physical Activity

    Författare :Elisabet Westerberg; Anna Rostedt Punga; Anne-Marie Landtblom; Chantal Tallaksen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Myasthenia Gravis; MG subgroups; Environmental factors; Lifestyle; Physical activity; Exercise; Clinical Neurophysiology; Klinisk neurofysiologi;

    Sammanfattning : Myasthenia Gravis (MG) is an autoimmune disease caused by antibodies directed against proteins at the neuromuscular junction (NMJ). The disturbed neuromuscular transmission induces fatigable weakness in skeletal muscles. LÄS MER

  3. 22. The Clinical and Pathological Spectrum of Idiopathic Inflammatory Myopathies : Implications for pathogenesis, classification and diagnosis

    Författare :Olof Danielsson; Jan Ernerudh; Magnus Vrethem; Göran Solders; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Background: Idiopathic inflammatory myopathies (IIM) constitute a heterogeneous group of diseases with severe consequences for the life of affected patients. Dermatomyositis, polymyositis and inclusion body myositis (IBM) are the classical representatives of this group. LÄS MER

  4. 23. The health economics of Duchenne muscular dystrophy

    Författare :Erik Landfeldt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Duchenne muscular dystrophy (DMD) is a rare neuromuscular disease characterized by progressive muscle degeneration resulting in loss of independent ambulation, serious multisystem complications, and a mean life expectancy at birth of about 25 years. Several therapies are on the horizon for DMD and it has thus become urgent to better understand the health economic context of the disease to enable assessments of cost-effectiveness and inform decisions regarding reimbursement of new health technologies. LÄS MER

  5. 24. Cellular and Molecular Mechanisms Underlying Acute Quadriplegic Myopathy : Studies in Experimental Animal Models and Intensive Care Unit Patients

    Författare :Holly Norman; Lars Larsson; Thomas Sejersen; Uppsala universitet; []
    Nyckelord :Neurosciences; Acute Quadriplegic Myopathy; intensive care unit; atrophy; myosin heavy chain; actin; myosin binding proteins; nuclear transcription factors; mRNA; Neurovetenskap;

    Sammanfattning : The combination of a severe systemic illness, corticosteroids, and neuromuscular blocking agents in patients on the mechanical ventilator often results in a condition known as Acute Quadriplegic Myopathy (AQM). While severe weakness of all spinal nerve innervated muscles is known to be a significant clinical characteristic of the disease, this symptom is typically not recognized until the disease has progressed to an advanced stage. LÄS MER

  7. 25. Mathematical modeling of the human smooth pursuit system

    Författare :Daniel Jansson; Alexander Medvedev; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Elektroteknik med inriktning mot reglerteknik; Electrical Engineering with specialization in Automatic Control;

    Sammanfattning : This licentiate thesis concerns mathematical modeling and identification of the the human smooth pursuit system (SPS) and the application of the models to motor symptom quantification in Parkinson's disease (PD).The SPS is a complex neuromuscular system governing smooth pursuit eye movements (SPEM), and the task is to keep a moving target in the visual field. LÄS MER