Sökning: "neuromuscular disease"
Visar resultat 16 - 20 av 64 avhandlingar innehållade orden neuromuscular disease.
16. Aspects on luminal nitric oxide in relation to oesophageal acid exposure and mucosal integrity
Sammanfattning : Nitric oxide (NO) exerts important neuromuscular control of the oesophagus, but little is known about the sources and effects of the NO present in the distal oesophageal lumen. These questions were presently addressed in both human and animal experiments. LÄS MER
17. T cells and costimulatory factors in myasthenia gravis
Sammanfattning : The autoimmune disease myasthenia gravis (MG) is characterized by muscle weakness due to a loss of acetylcholine receptors (AChR) at the neuromuscular end plate. Most MG patients have pathogenic antibodies directed against the receptor. We provide further evidence that T cells are important for establishment and continuation of the disease. LÄS MER
18. Molecular mechanisms of HLA associations with myasthenia gravis
Sammanfattning : Myasthenia gravis (MG) is a neuromuscular disease characterised by muscle weakness due to an autoimmune attack against the nicotinic acetylcholine receptor (nAChR). MG has a complex pattern of inheritance and several genetic and environmental factors are important in conferring susceptibility to the disease. LÄS MER
19. CTLA-4 expression, regulation and associations in autoimmune myasthenia gravis
Sammanfattning : Myasthenia gravis (MG) is a neuromuscular disease with muscle weakness due to an autoimmune attack against the nicotinic acetylcholine receptor (nAChR) on the skeletal muscle endplate. Cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) plays a global inhibitory role in the immune system and has a crucial role in autoimmunity. LÄS MER
20. Schizophrenia as a systemic disorder : studies of peripheral and central biological functions
Sammanfattning : Psychiatric disturbances with an onset in adulthood may show subtle signs in childhood and school age. This is particularly applicable to patients with schizophrenia. LÄS MER