Sökning: "neurodegencration"

Hittade 1 avhandling innehållade ordet neurodegencration.

1. 1. Functional studies of the ubiquitin proteasome system using GFP based reporters

   Författare :Kristina Lindsten; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Ubiquitin; proteasome; green fluorescent protein GFP ; degradation; inhibitor; Gly-Ala repeat; neurodegencration; poly-Gln aggregates.;

   Sammanfattning : Ubiquitin-dependent proteasomal degradation is of paramount importance for cellular processes such as cell cycle progression, transcriptional regulation, apoptosis and disposal of misfolded and aberrant proteins. Moreover the ubiquitin-proteasome system is the main producer of peptides used by major histocompatibility complex class 1 for antigen presentation. LÄS MER