Sökning: "neural crest"

Visar resultat 1 - 5 av 71 avhandlingar innehållade orden neural crest.

  1. 1. Neural crest in development and repair

    Författare :Jorge Benjamín Aquino; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis is focused on several aspects of neural crest biology, largely related to two main issues: 1) understanding its mechanisms of migration and 2) analyzing the potential of neural crest stem cells or their derivatives for nervous system repair. If repair is the aim, knowledge of both timing and events leading to axonal degeneration is required in order to block it and/or increase regeneration outcome. LÄS MER

  3. 2. The beneficial Effects of Neural Crest Stem Cells on Pancreatic      β–cells

    Författare :Anongnad Ngamjariyawat; Elena Kozlova; Leif Jansson; Jens Nielsen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neural Crest Stem Cells; Pancreatic Islets; β-cell proliferation; β-cell survival; Cadherin; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Patients with type-1 diabetes lose their β-cells after autoimmune attack. Islet transplantation is a co-option for curing this disease, but survival of transplanted islets is poor. Thus, methods to enhance β-cell viability and function as well as methods to expand β-cell mass are required. LÄS MER

  4. 3. Cell-matrix interactions in neural crest development

    Författare :Roberto Perris; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  5. 4. Neural stam cells, TLX, and Neuroblastoma

    Författare :Ravi Kanth Rao Saini; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; TLX; Neural Stem Cells; Dedifferentiation; DISC-1; DNA-PKcs;

    Sammanfattning : Neuroblastoma (NB) is one of the most commonly diagnosed extracranial tumors in children below five years of age. Moreover, NB accounts for almost 12-15% of all childhood cancer related fatalities. To date, the origin of NB has been linked to the neural crest derived sympathoadrenal progenitor cells. LÄS MER

  7. 5. Fate selection in the neural crest lineage and its regulation

    Författare :Natalia Akkuratova; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The neural crest is a transient embryonic progenitor cell population that generates a diverse array of cell and tissue types, including cartilage, bone, teeth, soft connective and adipose tissues, peripheral sensory and autonomic neurons, myelinating and non-myelinating Schwann cells, melanocytes, cardiac outflow tract, adrenal medulla and other derivatives. Neural crest cells start as neuroepithelial cells forming at the border of neural and non-neural ectoderm in a vertebrate embryo. LÄS MER