Sökning: "neoplasm metastasis"

Hittade 5 avhandlingar innehållade orden neoplasm metastasis.

  1. 1. Risk Factors of Tumour Recurrence and Reduced Survival in Rectal Cancer

    Författare :Fredrik Jörgren; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tumour Marker; Ezrin; Intestinal Perforation; Neoplasm Recurrence; Rectal Neoplasms; Local; Neoplasm Metastasis; Survival Rate; Risk Factors; Surgical; Anastomosis;

    Sammanfattning : In Sweden, 2000 patients are diagnosed with rectal cancer annually. In 1995, the Swedish Rectal Cancer Registry (SRCR) was launched to supervise and assure the quality of the management of rectal cancer. Advances in the management of rectal cancer have reduced the local recurrence (LR) rate and improved survival. LÄS MER

  3. 2. Interval cancers, positive predictive value for malignance and other early quality indicators in mammographic screening for breast cancer

    Författare :Bedrich Vitak; Ingvar Andersson; Linköpings universitet; []
    Nyckelord :Mammography; Breast neoplasm; Breast cancer screening; Interval breast cancer; Metastasis; Mortality; MEDICINE; MEDICIN;

    Sammanfattning : The study was designed to evaluate early quality indicators in screening for breast cancer. lt comprised, (i) investigations of compliance, recall, referral, cancer detection, and interval cancer rates in the Östergötland screening programme of women aged 40-74 years; (ii) evaluation of the three-stage diagnostic procedure for pre-operative assessment of women with suspicious mammographic findings; (iii) comprehensive analysis of all invasive interval cancers detected; and (iv) investigation into how to reduce the number of interval cancers without a concomitant increase in false positives. LÄS MER

  4. 3. New Roles of Filamins in Cell Signaling, Transcription and Organ Development

    Författare :Xianghua Zhou; Göteborgs universitet; []
    Nyckelord :filamins; cell movement; hypoxia-inducible factor 1; proto-oncogene proteins c-met; mice; knockout; F-actin-binding proteins; integrins; GTB phosphohydrolases; genetic diseases; inborn; vascular endothelial cell growth factor A; Smad2 protein; hepatocyte growth factor; cartilage; osteogenesis; neovascularization; neoplasm metastasis;

    Sammanfattning : Filamins are large actin-binding proteins that stabilize delicate three-dimensional actin networks and link them to cellular membranes. They integrate cell architectural and signaling functions and are essential for cell locomotion and development. LÄS MER

  5. 4. Pseudomyxoma Peritonei : Aspects of Natural History, Learning Curve, Treatment Outcome and Prognostic Factors

    Författare :Håkan Andréasson; Haile Mahteme; Lars Påhlman; Brendan Moran; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pseudomyxoma peritonei; Natural history; Learning curve; Cytoreductive surgery; Debulking surgery; Treatment outcome; Prognostic factors; PINCH;

    Sammanfattning : Pseudomyxoma peritonei (PMP) is a rare disease characterized by mucinous peritoneal metastasis (PM). Different loco-regional treatment strategies, i.e. debulking surgery and cytoreductive surgery (CRS) in combination with hyperthermic intraperitoneal chemotherapy (HIPEC), have changed the prognosis for these patients. LÄS MER

  7. 5. High-molecular-weight insulin-like growth factor 2 : immunohistochemical, ultrastructural and biochemical findings in insulin cells under normal, diabetic, and neoplastic conditions, and its role in non-islet cell tumour hypoglycaemia

    Författare :Anders Höög; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Insulin-like growth factor-2; IGF-2; islets of Langerhans; B-granules; Diabetes Mellitus type 2; insulinoma; Goto-Kakizaki rat; haemangiopericytoma; ultrastructural immunohistochemistry; gene expression.;

    Sammanfattning : IGF-2 immunoreactive (IR) cells were identified in the normal adult pancreas of man and rat and occurred exclusively in insulin-producing cells. When frozen human pancreatic tissue was extracted and gel-size-separated, a high-molecular-weight (HMW) IGF-2 peptide could be identified. LÄS MER