Sökning: "myeloid cells"

Visar resultat 1 - 5 av 316 avhandlingar innehållade orden myeloid cells.

  1. 1. Targeting residual malignant cells in myeloid leukemia

    Författare :Malin Nilsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute myeloid leukemia; chronic myeloid leukemia; histamine dihydrochloride; hydroxyurea; leukemic stem cells;

    Sammanfattning : Malignant cells persisting during treatment prevent cure in many patients with myeloid leukemia. In acute myeloid leukemia (AML), the failure to eradicate the leukemic clone during conventional chemotherapy is associated with leukemic relapse, mostly with dismal survival outcome. LÄS MER

  3. 2. Myeloid cells in autoimmune diseases

    Författare :Muhammad Sohel Mia; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple Sclerosis (MS) and Type 1 Diabetes (T1D) are autoimmune diseases caused by dysregulation of the immune system. Monocytes/macrophages are myeloid cells that play a pivotal role in both induction and resolution of these diseases depending on the stage and microenvironment of disease course. LÄS MER

  4. 3. Myeloid cells in experimental neuropathologies

    Författare :Melanie Pieber; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The first innate immune cells, most importantly for this thesis macrophages, microglia and eosinophils, were described more than 100 years ago and only now do we begin to understand more about their development, functions and properties. So while elimination of pathogens through phagocytosis (macrophages/microglia) or degranulation (eosinophils) were long considered as their main functions, research during the last decades has made it clear that innate immune cells do much more than maintain homeostasis in an organism. LÄS MER

  5. 4. Neutrophils as Suppressor Cells and their role in Multiple Myeloma

    Författare :Julia Westerlund; Myelomgruppen; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple myeloma; myelom; neutrophils; T-cells; immunology; suppressor cells; myeloid-derived suppressor cells;

    Sammanfattning : .... LÄS MER

  7. 5. Potential immunoregulatory role of T and dendritic cells in cancer : Investigations based on transcriptional analysis

    Författare :Milad Abolhalaj; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dendritic cells; T cells; head and neck cancer; acute myeloid leukemia; bladder cancer; T cell exhaustion;

    Sammanfattning : Cancer is a complex disease with various genetic and epigenetic driving factors. Cancer cells form a favored microenvironment to sustain their uncontrolled behavior leading to abnormal growth. With standard treatment including chemotherapy, relapse risk is high due to the resistance that cancer cells can develop against chemotherapy agents. LÄS MER