Sökning: "mycobacterial infections"

Visar resultat 1 - 5 av 23 avhandlingar innehållade orden mycobacterial infections.

  1. 1. Mucosal Immunity in Mycobacterial infections

    Författare :Anna Tjärnlund; Marita Troye-Blomberg; Andrzej Pawlowski; Anders Örn; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : More than a century after the identification of the tubercle bacillus and the first attempts at vaccination, tuberculosis (TB) still remains one of the world’s most serious infectious diseases. TB, caused by the bacterium Mycobacterium tuberculosis, is typically a disease of the lung, which serves both as port of entry and as the major site of disease manifestation. LÄS MER

  3. 2. Role of alveolar epithelial cells in macrophage responses against mycobacterial infections

    Författare :Olga Daniela Chuquimia Flores; Carmen Fernández; Diana Boraschi; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lung; alveolar epithelial cells; macrophages; AEC-derived media; control of intracellular bacterial growth; mycobacterial infections; immunologi; Immunology;

    Sammanfattning : This thesis aimed to investigate the role of alveolar epithelial cells (AEC) on immune responses against mycobacterial infections, specifically, the role of AEC in modulating macrophage functions through the secretion of broad variety of factors.In paper I, we compared murine AEC with interstitial macrophages (PuM) in their ability to take up and control mycobacterial growth and their capacity as antigen-presenting cells. LÄS MER

  4. 3. Role of SOCS proteins during mycobacterial infections

    Författare :Berit Carow; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mycobacterium tuberculosis is the world’s most successful bacterial killer. During infection, mycobacteria reside inside host cells encapsulated within a granuloma structure in the latent, asymptomatic phase of infection. Only 10% of latently infected develop active, infectious tuberculosis months or years after the initial infection. LÄS MER

  5. 4. Activation of neutrophils by mycobacteria and mycobacterial components

    Författare :Jenny Fäldt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human neutrophils; mycobacteria; oxygen radicals; cytokines; mycobacterial glycolipids; priming;

    Sammanfattning : The genus Mycobacterium includes free-living saprophytes, opportunists, and human pathogens.Mycobacterium tuberculosis, the organism causing tuberculosis, as well as other pathogenicmycobacteria can survive and multiply inside phagocytic cells, but the underlying mechanisms areonly partly understood. LÄS MER

  7. 5. Antimicrobial peptide therapy for tuberculosis infections

    Författare :Komal Umashankar Rao; Medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tuberculosis; antimicrobial peptides; mode of action; nanoparticles; novel therapy; membrane active peptides;

    Sammanfattning : Tuberculosis is a communicable disease that persists as a second leading cause for death, by an infectious agent. Several reasons contribute to this issue to this, of which an upsurge in antibiotic resistance is of top concern. Resistance patterns in the form of mono or multidrug resistance was reported to most clinical therapies at our disposal. LÄS MER