Sökning: "msp2"

Hittade 3 avhandlingar innehållade ordet msp2.

  1. 1. Genetic diversity of Plasmodium falciparum infections : influence on protective malaria immunity

    Författare :Sándor Bereczky; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Malaria; Plasmodium falciparum; genetic diversity; msp2; IgE; subsequent risk; asymptomatic; DNA extraction; ethnic group; spleen enlargement; hemoglobin;

    Sammanfattning : Detailed knowledge of the interaction between the human host and the antigenic and genetic diversity of Plasmodium falciparum infections is a prerequisite for understanding the mechanisms underlying acquisition of immunity to malaria. This thesis assessed the diversity of P. LÄS MER

  3. 2. Diversity and dynamics of Plasmodium falciparum malaria

    Författare :Anna Färnert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :malaria; Plasmodium falciparum; diversity; genotyping; PCR; msp1; msp2; glurp; dynamics; synchronicity; consistency; clinical protection; transmission; Tanzania; travellers;

    Sammanfattning : The epidemiology of genetic diversity of malaria parasites in relation to clinical parameters, acquisition of immunity and malaria transmission has implications for the development and evaluation of control measures such as vaccines and drugs. The diversity and dynamics of Plasmodium falciparum infections were therefore studied with a polymerase chain reaction (PCR)-based genotyping method targeting three highly polymorphic genes coding for potential vaccine candidate antigens: the two merozoite surface proteins msp1 block 2 and msp2 and the glutamine rich protein (glurp). LÄS MER

  4. 3. Functional antibody responses to the Plasmodium falciparum merozoite

    Författare :Hodan Ahmed Ismail; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Plasmodium falciparum is a leading cause of death among children under the age of five and pregnant women in sub-Saharan Africa. More than one third of the world’s population is at risk of contracting malaria, and 70 % of the cases are found in sub-Saharan Africa. LÄS MER