Sökning: "monocyte chemotactic protein-1"

Hittade 5 avhandlingar innehållade orden monocyte chemotactic protein-1.

  1. 1. Infectious and inflammatory mechanisms in preterm birth and cerebral palsy

    Författare :Bo Jacobsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; preterm birth; preterm labor; preterm prelabor rupture of membranes; intra-uterine infection; intra-amniotic inflammation; interleukin-6; interleukin-8; interleukin-18; monocyte chemotactic protein-1; cerebral palsy; antenatal risk factors; chorioamnionitis.;

    Sammanfattning : Background: International studies of women in preterm labor (PTL) and preterm pre-labor rupture of the membranes (pPROM) have shown a significant association between microbial invasion of the amniotic cavity (MIAC), some cytokines and chemokines and preterm birth (PTB). These studies have been performed in countries with higher incidence of PTB than that in Sweden. LÄS MER

  3. 2. NFAT signaling in chronic and acute inflammation - A novel target for the treatment of diabetic vascular complications and acute pancreatitis?

    Författare :Anna Zetterqvist; Diabetiska komplikationer; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NFAT; vascular; diabetes; inflammation; atherosclerosis; diabetic retinopathy; acute pancreatitis; osteopontin; VCAM-1; A-285222;

    Sammanfattning : Diabetic patients suffer from macro- and microvascular complications causing increased morbidity and mortality. How hyperglycemia provokes vascular damage remains unclear, but glucose is believed to fuel a harmful low-grade chronic inflammation of the vessel wall. LÄS MER

  4. 3. Experimental studies on effects of orthodontic forces in generation of immune responses : possible roles for immunoregulating molecules in the control of alveolar bone remodeling

    Författare :Najat AL-Sayed AL-Hashimi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Orthodontic forces; inflammation; immune responses; cytokines; chemokines.;

    Sammanfattning : The transformation of orthodontic forces to periodontal tissues involves several biological mechanisms, which ultimately result in bone remodelling. It has been suggested that the immune system plays a role in the regulation of bone remodelling through production of immune mediators by inflammatory cells that have migrated from dilated periodontal ligament capillaries after the application of orthodontic force. LÄS MER

  5. 4. Leukocyte dysfunction and inflammatory markers in patients with chronic kidney disease and patients on dialysis

    Författare :Jenny Olsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Patients with chronic kidney disease (CKD) and patients on dialysis are at risk for serious infectious complications. This is partly due to leukocyte dysfunction, which is a consequence of both uremic retention solutes and of dialysis. LÄS MER

  7. 5. Macro- and microvascular complications of diabetes: Studies on NFAT (Nuclear Factor of Activated T-cells) as a novel target for the treatment of atherosclerosis and vascular dysfunction in diabetes

    Författare :Fabiana Blanco; Diabetiska komplikationer; []
    Nyckelord :NFAT; VSMCs; Diabetes; Hyperglycemia; Aterosclerosis; Diabetic retinopathy; Oxidative stress;

    Sammanfattning : Diabetes is associated with devastating chronic complications including coronary heart disease and stroke (macrovascular complications) as well as microvascular disorders leading to damage of the small vessels and the development of retinopathy, nephropathy and neuropathy. The underlying pathogenesis is not clear, but hyperglycemia has been identified as an important risk factor. LÄS MER