Sökning: "mitochondrial metabolism"

Visar resultat 1 - 5 av 201 avhandlingar innehållade orden mitochondrial metabolism.

  1. 1. Mitochondrial Energy Metabolism : Kgd4 is a novel subunit of the α-ketoglutarate dehydrogenase complex

    Författare :Manfred Heublein; Martin Ott; Flavia Fontanesi; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; α-ketoglutarate dehydrogenase; Kgd4; Krebs cycle; Biochemistry; biokemi;

    Sammanfattning : Mitochondria are essential organelles of eukaryotic cells and are responsible for their energy metabolism. The citric acid cycle, a chain of redox reactions in the mitochondrial matrix, is a central metabolic hub. LÄS MER

  3. 2. Mitochondrial Iron Metabolism : Study of mitoferrin in Drosophila melanogaster

    Författare :Christoph Metzendorf; Maria Lind Karlberg; Kenneth Söderhäll; Martina Muckenthaler; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; iron; Drosophila; mitochondria; mitoferrin; ferritin; spermatogenesis; cell cycle; DFO; MRS12; Cell and molecular biology; Cell- och molekylärbiologi; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Sammanfattning : Iron has a dualistic character. On the one hand it is essential for the life of most organisms, on the other hand it is involved in the generation of reactive oxygen species that are implicated in diseases and aging. LÄS MER

  4. 3. Mitochondrial translation and its impact on protein homeostasis and aging

    Författare :Tamara Suhm; Martin Ott; Aleksandra Trifunovic; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mitochondrial ribosome; mitochondrial translation accuracy; mitochondrial communication; interorganellar communication; stress signaling; proteostasis; aging; yeast genetics; mitochondrial protein quality control; mitochondrial membrane protein insertion; Biochemistry; biokemi;

    Sammanfattning : Besides their famous role as powerhouse of the cell, mitochondria are also involved in many signaling processes and metabolism. Therefore, it is unsurprising that mitochondria are no isolated organelles but are in constant crosstalk with other parts of the cell. LÄS MER

  5. 4. Skeletal muscle fiber types in man : With special reference to anabolic signaling and mitochondrial bioenergetics

    Författare :Sebastian Edman; William Apro; Filip J Larsen; Abram Katz; Leigh Breen; Gymnastik- och idrottshögskolan; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mTORC1; THRIFTY; fiber type identification; muscle growth; aging; sarcopenia; mitochondrial function; oxphos; metabolism; Medicin Teknik; Medicine Technology;

    Sammanfattning : Human skeletal muscle consists of a mixture of slow-twitch (type I) and fast-twitch (type II) fibers. The type I fibers are endurance-oriented, with a metabolic system and infrastructure that supports aerobic metabolism. LÄS MER

  7. 5. On the antiporter-like subunits of respiratory chain Complex I - implications for the evolution and coupling mechanism of the NADH:quinone oxidoreductase enzyme complex

    Författare :Cecilie Mathiesen; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metabolism; Biokemi; metabolism; Biochemistry; mrp; electron transport; respiration; membrane protein;

    Sammanfattning : Complex I or NADH:quinone oxidoreductase is the largest enzyme complex, but the least understood energy coupling site in the respiratory chain of mitochondria and bacteria. No high-resolution structural information exists for this enzyme and the molecular mechanism that couples electron transfer and proton pumping is not understood. LÄS MER