Sökning: "mikrodialys"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet mikrodialys.

  1. 1. Intraocular Microdialysis

    Författare :Janina Waga; Lund Oftalmologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ophtalmology; pharmacokinetics; drug adminstration; vitreous body; Microdialysis; eye; Oftalmologi;

    Sammanfattning : The method of microdialysis has been adapted for ocular use. It is a technique for monitoring concentrations of different molecules in a tissue in vivo. It is based on the principle of diffusion through a semipermeable membrane. The membrane is mounted on a soft plastic shaft, connected to an inlet and an outlet tube. LÄS MER

  3. 2. Studies of the Biology of Intrathecal Treatment in Progressive MS

    Författare :Joakim Bergman; Anders Svenningsson; A. Tommy Bergenheim; Jonathan D. Gilthorpe; Joachim Burman; Magnus Andersson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Progressive Multiple Sclerosis; intrathecal treatment; Ommaya reservoir; anti-CD20 therapy; microdialysis; cerebrospinal fluid; CNS compartments; Progressiv Multipel Skleros; intratekal behandling; Ommaya reservoar; anti-CD20 terapi; mikrodialys; ryggmärgsvätska; sektioner i centrala nervsystemet; Neurology; neurologi;

    Sammanfattning : Background: Multiple Sclerosis (MS) is a chronic, inflammatory, autoimmune disease, affecting the central nervous system (CNS). About 85% of afflicted present with a relapsing-remitting form of the disease (RRMS), for which a breakthrough in treatment was made in 2008 with rituximab, an antibody directed towards CD20, a surface antigen on B-cells. LÄS MER

  4. 3. Bedside monitoring of cerebral energy metabolism using intracerebral microdialysis during neuro intensive care

    Författare :Nils Ståhl; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; neurofysiologi; Neurologi; neuropsychology; Neurology; glycerol.; glutamate; pyruvate; lactate; glucose; hyperglycaemia; intensive care; brain injury; Human; cerebral microdialysis; neurophysiology;

    Sammanfattning : In clinical situations with raised intracranial pressure (ICP) and impending insufficient cerebral blood flow (ischaemia), bedside information about energy metabolism in the brain would be helpful. Microdialysis is a technique that makes it possible to monitor the interstitial concentrations of various compounds in an organ. LÄS MER

  5. 4. Modeling and Simulation of Microdialysis in the Deep Brain Structures

    Författare :Elin Diczfalusy; Karin Wårdell; Mats Andersson; Joakim Wren; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Microdialysis is a method for monitoring of the local biochemical environment in a region of interest. The method uses a catheter, mimicking the function of a blood capillary, to sample substances from the surrounding medium through diffusion. LÄS MER

  7. 5. Porous Silicon -an enzyme coupling matrix for micromachined reactors

    Författare :Johan Drott; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Instrumentation technology; glucose; biosensor; immobilised enzyme; porous silicon; microreactor; Mät- och instrumenteringsteknik;

    Sammanfattning : The development of a miniaturised silicon wafer integrated enzyme reactor is described. The reactor was micromachined by anisotropic wet etching of (110) silicon. The enzyme glucose oxidase (GOx) was coupled to the reactor surface with standard methods of immobilising enzyme to silica. LÄS MER