Sökning: "microvascular reactivity"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden microvascular reactivity.

  1. 1. Systemic Lupus Erythematosus, with focus on vascular wall changes, cardiac risk-factor awareness and cardiovascular events

    Författare :Christine Bengtsson; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microvascular reactivity; arteria stiffness; cardiac risk factors; Cardiovascular event; SLE;

    Sammanfattning : Systemic Lupus Erythematosus is an autoimmune disease with a wide range of disease manifestations with respect to severity and magnitude of organ involvement. An increased risk of cardiovascular disease (CVD) compared with the general population causes both morbidity and mortality in SLE patients. LÄS MER

  2. 2. Assessment of microvascular effects of vasoactive drugs : Methodological in vivo studies in humansbased on iontophoresis

    Författare :Joakim Henricson; Folke Sjöberg; Gert Nilsson; Erik Droog Tesselaar; Jonas Åkeson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Cardiovascular disease is the leading cause of death in western societies and endothelial dysfunction is one of the earliest signs seen in the development of such conditions. Thedevelopment of prognostic tools to aid in the prediction of micro- and macrovascular diseasebased on assessment of vascular reactivity is therefore of paramount importance. LÄS MER

  3. 3. Local Purinergic Control of Arteriolar Reactivity in Pancreatic Islets and Renal Glomeruli

    Författare :Xiang Gao; Leif Jansson; Olle Hellberg; Uppsala universitet; []
    Nyckelord :afferent arteriole; islet arteriole; adenosine; A1 receptor; ATP; P2Y receptor; microperfusion; angiotensin II; type 2 diabetes; hypertension; oxidative stress; nitric oxide; tubuloglomerular feedback;

    Sammanfattning : Local control of regional blood flow is exerted mainly through the arterioles. An adequate minute-to-minute regulation of blood perfusion of the kidney and the pancreas is obtained by the modulation of arteriolar reactivity, which will influence the organ function. LÄS MER

  4. 4. Hemostasis and microvascular function in type 1 diabetes : effects of treatment with statin and aspirin

    Författare :Sara Tehrani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Patients with type 1 diabetes often develop microvascular complications and are at increased risk of premature cardiovascular disease. Women with type 1 diabetes lack the normal female protection against cardiovascular disease and may even be at higher risk compared with men with type 1 diabetes. LÄS MER

  5. 5. Platelet function in diabetes mellitus : relationships to hyperglycaemia, antidiabetic treatment and microangiopathy

    Författare :Marianne Yngen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Diabetes mellitus; platelet function; P-selectin; leukocyte-platelet cross-talk; endothelium; inflammation; coagulation; hyperglycaemia; metabolic control; microvascular complications; percutaneous coronary intervention.;

    Sammanfattning : Diabetes mellitus is associated with accelerated atherosclerosis and increased morbidity and mortality in micro-and macrovascular complications. The metabolic derangements that accompany diabetes can adversely influence platelets and vascular endothelial function, which may contribute to the pathogenesis of diabetic angiopathy. LÄS MER