Sökning: "microscopic polyangiitis"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden microscopic polyangiitis.

1. 1. Autoimmunity in glomerulonephritis; serological diagnosis and clinical outcome with special reference to Wegener´s granulomatosis and microscopic polyangiitis

   Författare :Kerstin Westman; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wegener´s granulomatosis; vasculitis; thyroid peroxidase antibodies; proteinase 3; myeloperoxidase; antineutrophil cytoplasmic antibodies; ANCA; thyroiditis; autoantibodies; glomerulonephritis; microscopic polyangiitis; Urology; nephrology; Urologi; nefrologi;

   Sammanfattning : Autoantibodies of different specificites have been described in association with glomerulonephritis and therefore the aim of this thesis was to improve our knowledge of the different manifestations of autoimmune phenomena which are involved in the glomerulonephritides. Special reference is made to Wegener´s granulomatosis (WG) and microscopic polyangiitis (MP) which are frequently associated with the prevalence of anti-neutrophil cytoplasmic antibodies (ANCA). LÄS MER

3. 2. Studies on the Epidemiology and Outcome of Primary Systemic Vasculitis

   Författare :Aladdin Mohammad; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; polyarteritis nodosa; survival; microscopic polyangiitis; arteritis; vasculitis damage index; Vasculitis; ANCA; Wegener s granulomatosis; Churg-Strauss syndrome;

   Sammanfattning : Primary Systemic Vasculitides [PSV: Wegener's granulomatosis (WG), microscopic polyangiitis (MPA), Churg-Strauss syndrome (CSS) and polyarteritis nodosa (PAN)] are rare systemic diseases of unknown etiology; if untreated, they are associated with high morbidity and mortality rates. Changes in the classification and diagnostic improvements during the last decades have increased reported prevalence and incidence rates of PSV. LÄS MER

4. 3. Diagnostic and prognostic aspects of anti-neutrophil cytoplasmic antibodies in systemic vasculitis

   Författare :Daina Selga; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; serologi; serology; epitope; Wegener s granulomatosis; microscopic polyangiitis; polyarteritis nodosa; capture ELISA; Immunology; anti-neutrophil cytoplasmic antibody; proteinase 3; vasculitis; nephrology; Urologi; nefrologi; Urology;

   Sammanfattning : Primary systemic vasculitis is associated with a high mortality if left untreated and it is essential to make the diagnosis before permanent organ damage has occurred. In this thesis the diagnostic and prognostic significance of anti-neutrophil cytoplasmic antibodies (ANCA) in systemic vasculitis is investigated. LÄS MER

5. 4. The Importance of Demographic and Geographical Factors on the Incidence and Outcome of Systemic Small Vessel Vasculitis Associated with Anti-Neutrophil Cytoplasmic Antibodies

   Författare :Maria Weiner; Mårten Segelmark; Per Eriksson; Øyvind Palm; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) comprise microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA) and eosinophilic granulomatosis with polyangiitis (EGPA). Two serotypes are recognized: myeloperoxidase (MPO)-ANCA and proteinase 3 (PR3)-ANCA. LÄS MER

7. 5. Immunological studies on anca-associated vasculitis with special reference to T cell activation

   Författare :Marta Christensson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : This thesis focuses on the role of T cells in ANCA-associated vasculitis. We initially investigated activation markers on T cells in patients with Wegener's granulomatosis (WG), microscopic polyangiitis (MPA) and renal limited disease (RLD) and found increased expression indicating continuous activation despite clinical remission. LÄS MER