Sökning: "microsatellite"

Visar resultat 1 - 5 av 154 avhandlingar innehållade ordet microsatellite.

  1. 1. Bioinformatic Analysis of Mutation and Selection in the Vertebrate Non-coding Genome

    Författare :Mikael Brandström; Hans Ellegren; Diethard Tautz; Uppsala universitet; []
    Nyckelord :Biology; non-coding genome; selection; mutation; chicken; human; indel; microsatellite; sequence alignment; comparative genomics; bioinformatics; vertebrate; Biologi;

    Sammanfattning : The majority of the vertebrate genome sequence is not coding for proteins. In recent years, the evolution of this noncoding fraction of the genome has gained interest. These studies have been greatly facilitated by the availability of full genome sequences. LÄS MER

  3. 2. Approaches for analysis of mutations and genetic variations

    Författare :Afshin Ahmadian; KTH; []
    Nyckelord :LOH; microsatellite; fragment analysis; DNA sequencing; pyrosequencing; cancer; mutation; variation; SNP; allele-specific extension; apyrase; TECHNOLOGY; TEKNIKVETENSKAP;

    Sammanfattning : Detecting mutations and genomic variations is fundamental indiagnosis, isolating disease genes, association studies,functional genomics and pharmacogenomics. The objective hasbeen to use and further develop a variety of tools andtechnologies to analyze these genetic alterations andvariations. LÄS MER

  4. 3. Disentangling small genetic differences in large Atlantic herring populations: comparing genetic markers and statistical power

    Författare :Lena C. Larsson; Linda Laikre; Nils Ryman; Lorenz Hauser; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; conservation genetics; marine fish; spatial and temporal genetic variation; molecular marker comparison; allozyme; microsatellite; selection; fisheries management; Biology; Biologi; populationsgenetik; Population Genetics;

    Sammanfattning : Genes are the foundation of evolution and biodiversity. The genetic structure of natural populations needs to be understood to maintain exploited resources rationally. This thesis focuses on genetic variability and methods to determine spatial and temporal genetic heterogeneities. LÄS MER

  5. 4. Dispersal, inbreeding and fitness in natural populations

    Författare :Bengt Hansson; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; immigration; inbreeding; inbreeding depression; heterozygosity; microsatellite; great reed warbler; bird; Djurekologi; Animal ecology; philopatry; heritability; founder event; dispersal; bottleneck;

    Sammanfattning : To evaluate how inbreeding affects the viability of small populations, it is crucial to determine what constitutes a population (i.e., the number of breeders in local patches and the degree of dispersal), and also to estimate the reproductive consequences of philopatry and emigration. LÄS MER

  7. 5. Development and Application of Genomic Resources in Non-model Bird Species

    Författare :Biao Wang; Jacob Höglund; Christopher Wheat; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; genome; transcriptome; next generation sequencing; non-model species; bioinformatics; reference guided assembly; RNA-Seq; comparative genomics; gene expression; major histocompatibility complex; single nucleotide polymorphism; microsatellite; Biologi; Biology;

    Sammanfattning : Understanding the genetic basis of biological processes is a fundamental component of modern ecology and evolutionary biology studies. With the recent advent of next generation sequencing (NGS) technologies, it is now possible to perform large genome and transcriptome projects for ecologically important non-model species. LÄS MER