Sökning: "metabolic activity assay"

Visar resultat 1 - 5 av 44 avhandlingar innehållade orden metabolic activity assay.

1. 1. Ligands of the Angiotensin II Type 2 Receptor : Exploring structure and function of the AT2R ligand C38

   Författare :Rebecka Isaksson; Mats Larhed; Annette Bayer; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiotensin II type 2 receptor; AT2R antagonists; sulfonyl carbamates; bicyclic amides; metabolic stability; functional activity assay; pharmacological profile; medicinal chemistry; structure-activity relationship; Medicinal Chemistry; Läkemedelskemi;

   Sammanfattning : The renin-angiotensin-aldosterone-system (RAAS) control blood-pressure regulation, exerted by the main effector peptide angiotensin II (AngII) binding the angiotensin II type 1 receptor (AT1R). While hypertension is the most known disease caused by over-activity in RAAS, several proteins in the system exhibit protective functions. LÄS MER

3. 2. Effect of surface characteristics on cellular adherence and activity

   Författare :Marjan Dorkhan; Malmö högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bacteria; microbial biofilm; dental implant; streptococci; oral bacteria; salivary pellicle; early colonizers; titanium oxide; microbial activity; oral keratinocytes; gingival fibroblasts; cell attachment; surface modification; anodic oxidation; anatase;

   Sammanfattning : Ersättning av förlorade tänder med tandimplantat är numera en vanlig behandlingsmetod med generellt goda resultat. Antalet implantatsystem på den internationella marknaden har ökat kraftigt under senare år. LÄS MER

4. 3. Gill EROD Activity in Fish : A Biomarker for Waterborne Ah-receptor Agonists

   Författare :Alexandra Abrahamson; Ingvar Brandt; Björn Brunström; Janneche Utne Skaare; Uppsala universitet; []
   Nyckelord :Biology; biomarker; fish; gill; CYP1A; EROD; environmental monitoring; induction; inhibition; PAH; PCB; produced water; Biologi;

   Sammanfattning : Induction of the cytochrome P450(CYP)1A protein and the connected increase in 7-ethoxyresorufin O-deethylase (EROD) activity are common biomarkers in fish. Enhanced activity of this protein signals exposure to Ah-receptor agonists such as chlorinated dioxins, co-planar polychlorinated biphenyls (PCBs) and certain polycyclic aromatic hydrocarbons (PAHs). LÄS MER

5. 4. Regulation of Lipoprotein Lipase Activity : an In-vitro Study of a Complex and Dynamic System

   Författare :Oleg Kovrov; Gunilla Olivecrona; Aivar Lookene; Mikael Larsson; Geesje Dallinga-Thie; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Triglyceride Metabolism; Lipoprotein lipase; Angiopoietin-Like Proteins; Apolipoproteins; Isothermal titration calorimetry; Biochemistry; biokemi; molekylärbiologi; Molecular Biology;

   Sammanfattning : The progress of human society outpaces our biological evolution, and this brings unexpected health problems. The industrial revolution brought up dramatic changes in nutrition and lifestyle – we are increasingly shifting towards a nutrient-rich Western-patterned diet and to a sedentary lifestyle. LÄS MER

7. 5. Titanium Dioxide Photocatalysis in Biomaterials Applications

   Författare :Yanling Cai; Ken Welch; Maria Strømme; Håkan Engqvist; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; titanium dioxide; photocatalysis; bioactivity; antibacterial effect; metabolic activity assay; biofilm; reactive oxygen species; disinfection kinetics; post-UV;

   Sammanfattning : Despite extensive preventative efforts, the problem of controlling infections associated with biomedical materials persists. Bacteria tend to colonize on biocompatible materials and form biofilms; thus, novel biomaterials with antibacterial properties are of great interest. LÄS MER