Sökning: "low MBL"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden low MBL.

  1. 1. The PD-1 pathway and the complement system in systemic lupus erythematosus

    Författare :Helga Kristjánsdóttir; Marta E Alarcón-Riquelme; Kristján Steinsson; Tom W J Huizinga; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; SLE; autoimmune diseases; PD-1; C4AQ0; low MBL; multicase family; Immunology; Immunologi; medicinsk genetik; Medical Genetics;

    Sammanfattning : Autoimmune diseases occur in up to 3-5% of the general population and represent a diverse collection of diseases with regards to clinical manifestations. The unifying factor of autoimmune diseases is tissue and organ damage as a result of an immune response mounted against self-antigens. LÄS MER

  3. 2. Aerosol impacts on subtropical low-level clouds: a satellite and modelling perspective

    Författare :Alejandro Baró Pérez; Annica M.L. Ekman; Frida A.-M. Bender; Abhay Devasthale; Jens Redemann; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Aerosol-cloud-radiation interactions; cloud microphysics; biomass burning; stratocumulus to cumulus transition; cloud radiative effect; Atmospheric Sciences and Oceanography; atmosfärvetenskap och oceanografi;

    Sammanfattning : Complex interactions between aerosols, clouds, and radiation impact Earth's climate. However, several aspects of these interactions remain uncertain, which has led to extensive research over the last decades. LÄS MER

  4. 3. Recognition molecules of the complement system: C1q and mannan-binding lectin in autoimmunity and immune defence

    Författare :Ulla Mårtensson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serologi; Immunologi; Immunology; serology; autoantibodies; collectins; complement; autoimmunity; Infections; Infektioner;

    Sammanfattning : The C1 subcomponent C1q and the mannan-binding lectin (MBL) are recognition proteins of the complement system, and have similar structure. C1q binds to IgG and IgM and activates the classical pathway. MBL binds to carbohydrate structures and activates the lectin pathway. LÄS MER

  5. 4. Myocardial infarction and diabetes mellitus : studies on glucose lowering therapies and novel risk markers based on observations from the DIGAMI 2 trial

    Författare :Linda Garcia Mellbin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Patients with myocardial infarction (MI) and type 2 diabetes (T2DM) and have a poor prognosis. Hyperglycemia is an independent risk predictor. The best tools for glucose control are debated. Important is identification of biomarkers to gain further pathophysiological insights and new therapeutic possibilities. LÄS MER

  7. 5. Severe sepsis : epidemiology and sex-related differences in inflammatory markers

    Författare :Sofie Jacobson; Ola Winsö; Stefan Söderberg; Peter Larsson; Else Tönnesen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Severe sepsis; Leptin; Adiponectin; Mannose-binding lectin; Sex; anestesiologi; Anaesthesiology;

    Sammanfattning : Background.  Sepsis is a syndrome associated with high mortality rates, substantial morbidity and high costs of care. The incidents of sepsis is reported to be high and controversy exists whether gender affect severity or outcome. LÄS MER