Sökning: "lipoprotein a"

Visar resultat 6 - 10 av 305 avhandlingar innehållade orden lipoprotein a.

  1. 6. Serum lipoprotein(a) in relation to ischemic heart disease and associated risk factors

    Författare :Lisbeth Slunga; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipoprotein a ; lipids; epidemiology; coronary artery disease; coronary angiography; HLA DR; acute-phase protein; myocardial infarction; HMG CoA reductase inhibitor; simvastatin;

    Sammanfattning : Lipoprotein(a) (Lp(a)) consists of an LDL-like particle and the specific protein apo(a), which is very similar to plasminogen. Apo(a) contains repeated kringle structures and a serine protease domain, which cannot be activated by t-PA. Lp(a) is considered to be a predictor for atherosclerotic disease. LÄS MER

  3. 7. Risk markers for a first myocardial infarction

    Författare :Anna Margrethe Thøgersen; Annika Rosengren; Umeå universitet; []
    Nyckelord :haemostatis; lipoprotein a ; MTHFR; homocysteine; proinsulin; leptin; apolipoprotein A1; DHEAS; myocardial infarction; risk factors;

    Sammanfattning : The development of a first myocardial infarction is associated with a large number of contributing factors. Age, male sex, hypertension, smoking, diabetes, body mass index and hypercholesterolemia are considered as established risk factors. LÄS MER

  4. 8. Lipoprotein lipase-unstable on purpose?

    Författare :Liyan Zhang; Gunilla Olivecrona; Cecilia Holm; Umeå universitet; []
    Nyckelord :Biochemistry; Lipoprotein lipase; Apolipoprotein CII; dimerization; monomerization; Molecular chaperones; Biokemi;

    Sammanfattning : Lipoprotein lipase (LPL) is a central enzyme in lipid metabolism. It is a non-covalent, homodimeric and N-glycosylated protein, which is regulated in a tissue-specific manner and is dependent on an activator protein, apolipoprotein CII. Dissociation of active LPL dimers to monomers leads to loss of activity. LÄS MER

  5. 9. Effects of growth hormone on cardiovascular risk factors and atherosclerosis

    Författare :Maria Leonsson Zachrisson; Göteborgs universitet; []
    Nyckelord :growth hormone; pituitary deficiency; dietary fat; cholesterol; low density; lipoprotein; intima-media thickness; IL-6; CRP; TNF-á;

    Sammanfattning : Hypopituitary patients with growth hormone (GH) deficiency (GHD) have increasedmorbidity and mortality from cardiovascular disease (CVD). GH treatment has both beneficialand potentially negative cardiovascular effects. LÄS MER

  7. 10. Novel factors affecting clearance of triacylglycerol-rich lipoproteins from blood

    Författare :Stefan K Nilsson; Gunilla Olivecrona; Aivar Lookene; Ko Willems van Dijk; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lipoprotein; triacylglycerol; apolipoprotein A-V; ANGPTL; Cardiovascular medicine; Kardiovaskulär medicin; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Apolipoprotein (apo) A-V is the most recently discovered member of a protein family responsible for the structure and metabolic fate of plasma lipoproteins. While most of the apolipoproteins are well characterized with regard to structure, interactions and function, the role of apoA-V is not well understood. LÄS MER