Sökning: "lipoma"

Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet lipoma.

1. 1. Genetic Characterization of Bone and Soft Tissue Tumors

   Författare :Anna Dahlen; Avdelningen för klinisk genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; Klinisk genetik; cytogenetik; Genetik; cytogenetics; mesenchymal tumor; pericytoma; Genetics; chondroma; lipoma;

   Sammanfattning : Bone and soft tissue tumors (BSTT) constitute a heterogeneous group of neoplasms of mesenchymal and neuroectodermal origin. Although many BSTT are rare, it has become clear that BSTT are characterized by recurrent acquired chromosomal aberrations, and the general aim of this thesis have been to apply molecular genetic and molecular cytogenetic techniques to further characterize recurrent breakpoints and deletions, and to search for candidate target genes. LÄS MER

3. 2. Fine needle aspiration diagnosis of spindle cell tumors of soft tissue, including the use of ancillary methods, and correlation with clinical data

   Författare :Henryk Domanski; Tumörmikromiljö; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Patologi allmän ; patologisk anatomi; General pathology; pathological anatomy; spindle cell lipoma; soft tissue; spindle cell tumors; Medicine human and vertebrates ; Medicin människa och djur ; schwannoma; neurilemoma; leiomyosarcoma; immunocytochemistry; FNA; fine needle aspiration; dermatofibrosarcoma protuberans; elastofibroma dorsi; Cytology; electron microscopy;

   Sammanfattning : Fine needle aspiration cytology (FNAC) is gaining increased popularity in the diagnosis of soft tissue lesions. FNAC used as a primary examination method to obtain a morphologic diagnosis, has been part of the diagnostic work-up of patients admitted to the Musculoskeletal Tumor Center of the Lund University Hospital since 1972. LÄS MER

4. 3. Regulation of the vascular smooth muscle cell phenotype

   Författare :Henrik Lindskog; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; embryonic stem cells; vascular smooth muscle cell; smooth muscle cell; pericyte; phenotypic modulation; lipoma preferred partner; ectra-cellular matrix; zinc finger protein 148;

   Sammanfattning : Smooth muscle cells (SMC) are present in many internal organs such as the blood vessels and the gastrointestinal channel. Their main functions are to provide stability to the tissue and to provide contractile capability. SMC are not terminally differentiated but can switch between several phenotypes, which is also known as phenotypic modulation. LÄS MER

5. 4. Developmental origin and molecular regulation of vascular smooth muscle cells

   Författare :Per Wasteson; Göteborgs universitet; []
   Nyckelord :smooth muscle cell; aorta; cell origin; lateral plate mesoderm; paraxial mesoderm; lipoma preferred partner; serum response factor; neointimal hyperplasia; angiotensin II; platelet-derived growth factor-B;

   Sammanfattning : Several pathologies of the vascular system have been suggested to be dependent on the smooth muscle cells (SMCs) that build up the vessel wall. Aortic SMCs have been proposed to derive from lateral plate mesoderm. LÄS MER

7. 5. CYTOGENETIC AND MOLECULAR GENETIC CHARACTERIZATION OF LIPOMAS

   Författare :Hammurabi Bartuma; Avdelningen för klinisk genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; soft tissue tumors; adipocytic tumors; conventional lipomas; spindle cell lipoma; HMGA2; cytogenetic; molecular genetic; SNP array; GGE;

   Sammanfattning : The focus of this thesis was to study cytogenetic and molecular genetic aberrations in lipomas. For this purpose, chromosome banding analysis, fluorescence in situ hybridization (FISH), as well as high resolution single nucleotide polymorphism (SNP)–arrays were used to identify recurrent chromosomal aberrations in lipomas. LÄS MER