Sökning: "ligand synthesis"
Visar resultat 11 - 15 av 206 avhandlingar innehållade orden ligand synthesis.
11. Development and application of new chiral -amino alcohols in synthesis and catalysis : Use of 2-azanorboryl-3-methanols as common intermediates in synthesis and catalysis
Sammanfattning : The development and application of unnatural amino alcohols,prepared via hetero-Diels-Alder reactions,in synthesis and catalysis is described.The studies are concerned with the [i]scope of the hetero-Diels-Alder reaction and preparation of important intermediates in the synthesis of antiviral agents,[ii ]application of amino alcohols in the ruthenium transfer hydrogenation of ketones,[iii ]use of similar precursors in the in situ generation of oxazaborolidines for reduction of ketones,and [iv] development and application of new chiral auxiliaries for dialkylzinc additions to activated imines, respectively. LÄS MER
12. Platinum(II) and Palladium (II) Complexes with Group 14 and 15 Donor Ligands. Synthesis, Structure and Substitution Mechanisms
Sammanfattning : The present thesis deals with Pd(II) and Pt(II) complexes with group 14 and 15 donor ligands. Such complexes have been prepared and investigated mainly with regard to their ground state structures and the mechanism according to which they undergo substitution. LÄS MER
13. Design, Synthesis and Properties of Bipyridine-capped Oligothiophenes for Directed Energy and Electron Transfer in Molecular Electronic Applications
Sammanfattning : The earliest landmark in computer technology was construction of the Electronic Numerial Integrator and Computer, ENIAC. Computational switching was performed with vacuum tubes and relays, rather large in size, making this computer rather unwieldy. LÄS MER
14. Multivariate design of molecular docking experiments : An investigation of protein-ligand interactions
Sammanfattning : To be able to make informed descicions regarding the research of new drug molecules (ligands), it is crucial to have access to information regarding the chemical interaction between the drug and its biological target (protein). Computer-based methods have a given role in drug research today and, by using methods such as molecular docking, it is possible to investigate the way in which ligands and proteins interact. LÄS MER
15. Synthesis and Applications of P-chirogenic Phosphine Boranes
Sammanfattning : AbstractThis thesis reports the independent synthesis of both enantiomers of P-chirogenic phosphine ligands and the building blocks thereof, which are suitable for parallel synthesis efforts and for the generation of more diverse libraries of P-chirogenic compound. The use of P-chirogenic phosphine boranes in transition metal-catalyzed reactions, such as palladium-catalyzed allylic alkylation and amination, is also described. LÄS MER