Sökning: "life-threatening arrhythmia"
Visar resultat 1 - 5 av 6 avhandlingar innehållade orden life-threatening arrhythmia.
1. Health-related quality of life in recipients with an implantable cardioverter defibrillator due to life-threatening arrhythmias : a 5 year follow-up
Sammanfattning : The general aim of this thesis was to describe self-reported health-related quality of life (HRQoL) in recipients with an implantable cardioverter defibrillator (ICD) due to life-threatening arrhythmias over a 5-year period. The design was prospective and longitudinal. LÄS MER
2. Long QT syndrome in Sweden : founder effects and associated cardiac phenotypes
Sammanfattning : Background: We aimed to increase the knowledge regarding the familial arrhythmogenic disorder Long QT Syndrome (LQTS) and its recessive variant Jervell and Lange-Nielsen Syndrome (JLNS) in Sweden, including prevalences and clinical phenotypes. A specific focus was directed towards two KCNQ1 mutations –p.Y111C and p. LÄS MER
3. Applications of Vectorcardiography for Diagnosis and Risk Stratification in Subpopulations at Risk for Life-Threatening Arrhythmias
Sammanfattning : Introduction: Vectorcardiography, or 3-dimensional electrocardiography is a tool which can be used to identify subtle changes in the electrical forces of the heart, and which can be applied to atrial depolarization, ventricular depolarization and ventricular repolarization for prognostic and diagostic purposes. Methods: Kor’s regression-related and quasi orthogonal methods was used to derive vectorcardiographic parameters from the 12-lead electrocardiogram and applied to a cohort of cryptogenic stroke patients to assess atrial fibrillation, hypertrophic cardiomyopathy patients to assess for ventricular arrhythmias, applied with right-precordial directed quasi orthogonal method to arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC/D) patients for diagnosis, and applied to ventricular repolarization only to patients with genotype-positive/phenotype-negative Long QT2 syndrome (KNCH2 mutation) to assess for cardiac events. LÄS MER
4. Catching broken hearts - Electrocardiography and in-hospital outcome in Takotsubo syndrome versus ST elevation myocardial infarction
Sammanfattning : BACKGROUND AND AIMS: Takotsubo syndrome (TS) and acute myocardial infarction (AMI) have similar symptoms, non-invasive test results and complications. Whereas AMI is caused by cardiac ischemia, the pathophysiology of TS is incompletely understood. LÄS MER
5. Role of the hERG-channel in arrhythmia and teratogenicity : studies in animal models and the human embryonic heart
Sammanfattning : Background: Drugs that inhibit cardiac repolarization are associated with potentially life threatening side effects in the form of ventricular arrhythmias in humans. Animal studies show that this mechanism also is relevant for the embryo, and that the circulatory depression results in hypoxia with embryotoxicity in the form of malformations and death as a consequence. LÄS MER