Sökning: "leukaemia"

Visar resultat 1 - 5 av 112 avhandlingar innehållade ordet leukaemia.

  1. 1. Characterisation of the leukaemia-associated ETO homologues

    Författare :Sofia Rondin Lindberg; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Haematology; SIN3B; corepressor; MTGR1; MTG16; ETO; AML1-ETO; AML; haematopoiesis; leukaemia; Hematologi; extracellulära vätskor;

    Sammanfattning : Acute myeloid leukemia (AML) is commonly associated with balanced chromosomal translocations. Characteristically, these translocations lead to the fusion of two unrelated genes, resulting in the expression of an aberrant fusion protein. t(8;21) is one of the most common translocations found in patients with AML. LÄS MER

  3. 2. Living with leukaemia : studies on quality of life, interaction and caring

    Författare :Carina Berterö; Gertrud Grahn; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Leukaemia is one form of cancer disease, comprising both an acute or chronic form, and has a wide range of altemative therapy aids, as well as a highly unpredictable prognosis. This thesis is a study of 27 patients with acute and chronic leukaemia. LÄS MER

  4. 3. Acute lymphoblastic leukaemia : studies on prognosis and effects of treatment with special reference to adults

    Författare :Bengt Smedmyr; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  5. 4. Modeling normal and malignant hematopoiesis in vitro. To screen for extrinsic regulators and differentiation therapy

    Författare :Simon Hultmark; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; acute myeloid leukaemia; Hematologi; stem cells; differentiation induction; leukaemia; treatment; small molecule drugs; PKC; FLT3; shRNA; small molecule inhibitor; Small Molecule Libraries; MEK ERK pathway; natural product; co-culture; drug screening; combination therapy;

    Sammanfattning : The incredible thing with blood stem cells, also known as hematopoietic stem cells (HSC), is that they can restore normal hematopoiesis in patients that need a new blood system. Since a prerequisite for successful transplantation is immune compatibility, it requires large donor registries to find a suitable match for a recipient. LÄS MER

  7. 5. Epidemiological aspects on hairy cell leukaemia

    Författare :Marie Nordström; Håkan Olssen; Linköpings universitet; []
    Nyckelord :Hairy cell leukaemia; case-control study; occupational exposures; Epstein-Barr virus; medical histmy; organochlorines; MEDICINE; MEDICIN;

    Sammanfattning : Non Hodgkin's lymphoma (NHL) has an increasing incidence in many Western countries. In Sweden, about 1800 new cases were reported to the Cancer Registry in 1996 including cases of chronic lymphatic leukaemia (CLL). Hairy cell leukaemia (HCL) is a rare subgroup of malignant lymphoma. About 25 new cases are diagnosed among males in Sweden yearly. LÄS MER