Sökning: "lectin"

Visar resultat 1 - 5 av 113 avhandlingar innehållade ordet lectin.

1. 1. Proteoglycan Lectin Domain Interactions in Extracellular Matrix Assembly

   Författare :Anders Olin; Infektionsmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper allmänt ; General biomedical sciences; crystal structure; network formation; collagen IX; N-glycans; PRELP; cross-linking; fibulin-2; lectin; G3; ECM; proteoglycan;

   Sammanfattning : This thesis focuses on the C-terminal G3 region of the large aggregating proteoglycans that are found in complex with hyaluronan in the extracellular matrix. The G3 region contains a C-type lectin domain that binds different extracellular matrix proteins playing an integral role in tissue organization during development and remodeling. LÄS MER

3. 2. Carbohydrate-Functionalized Nanomaterials : Synthesis, Characterization and Biorecognition Studies

   Författare :Na Kong; Mingdi Yan; Joseph J. Barchi Jr; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carbohydrate; glyconanomaterials; perfluorophenyl azide PFPA ; CuAAC; AAAC; coupling chemistry; 19 F q NMR; lectin; carbon nanomaterials; microwave irradiation; Kemi; Chemistry; Bioteknologi; Biotechnology;

   Sammanfattning : This thesis focuses on the development of carbohydrate coupling chemistry on nanomaterials and their biological activity studies. It is divided into two parts:In part one, two carbohydrate immobilization approaches, based on perfluorophenyl azide (PFPA)-functionalized silica nanoparticles (SNPs), are presented, where the binding affinity of the glyconanoparticles was evaluated through carbohydrate-lectin interaction. LÄS MER

4. 3. Multifunctional Glyconanomaterials : Applications in Biorecognition and Drug Delivery

   Författare :Zhou Juan; Ramström Olof; Ravin Narain; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; glyconanomaterials; cellulose nanocrystals; chitin nanocrystals; mesoporous silica nanoparticles; lectin; biorecognition; drug delivery; bacteria; cytotoxicity; perfluorophenylazide; fluorescent dye; carbohydrate ligands.;

   Sammanfattning : This thesis consists of three parts, which revolve around the fabrication of multifunctional glyconanomaterials (cellulose nanocrystals, chitin nanocrystals, mesoporous silica nanoparticles) and the development of their applications in biorecognition and nanomedicine.Part one presents a detailed introduction to glyconanomaterials, focusing on cellulose nanocrystals, chitin nanocrystals and mesoporous silica nanoparticles, including their general preparations, properties and applications. LÄS MER

5. 4. Developmental and methodological aspects of intestinal and pancreatic function in pigs and rats

   Författare :Klas Rådberg; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; macromolecule; endocytosis; FITC-dextran; secretion; mucosa; CCK; pancreas; disaccharidase; intestinal permeability; lectin; morphometry; Animal physiology; Djurfysiologi;

   Sammanfattning : The gastrointestinal tract has two opposing functions; to effectively absorb nutrients and to act as a safety barrier against hazardous substances in the environment. After birth these functions develops gradually. LÄS MER

7. 5. From Structure to Function with Binding Free Energy Calculations for Codon Reading, Riboswitches and Lectins

   Författare :Johan Sund; Åqvist Johan; Javier Luque; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; binding free energy; ribosome; codon reading; release factor; mitochondrial translation; purine riboswitch; lectin; molecular dynamics; free energy perturbation; Biology with specialization in Structural Biology; Biologi med inriktning mot strukturbiologi;

   Sammanfattning : Molecular association is part of many important processes in living cells. Computational methods for calculating binding free energies allows for a quantitative examination of biomolecular structures and hypotheses drawn from biochemical experiments. LÄS MER