Sökning: "ion-channel"
Visar resultat 1 - 5 av 83 avhandlingar innehållade ordet ion-channel.
1. Ion channel control of phasic insulin secretion
Sammanfattning : Glucose-stimulated insulin secretion exhibits a biphasic pattern. The mechanism underling biphasic insulin secretion is not fully understood, but consensus exists that an elevation in [Ca2+]i is required for both first- and second-phase insulin secretion. LÄS MER
2. Polyunsaturated Fatty Acids Modifying Ion Channel Voltage Gating
Sammanfattning : Voltage-gated ion channels play fundamental roles in neuronal excitability and therefore dysfunctional channels can cause disease. Epilepsy is such a disease, affecting about 1% of the population and being characterized by synchronous electric activity of large groups of neurons leading to various types of seizures. LÄS MER
3. Novel microfluidic methods for studies of ion channel function
Sammanfattning : .... LÄS MER
4. Studies of ligand- and temperature-gated ion channels using microfluidic methods
Sammanfattning : This thesis describes the studies of the GABAA receptor, a ligand-gated ion channel, and the ligand- and temperature-gated ion channel TRPV1. The desensitization behavior of both of these proteins has been studied for different conditions, using a microfluidic device for superfusion. LÄS MER
5. A Solution Exchange Platform for Exposure of Cells to Chemical Waves
Sammanfattning : This thesis presents the development, characterization and suggested applications of a platform for controlling the chemical environment around a cell or a cell constituent. The platform is unique in its capability to combine rapid solution switching with precise timing and access to a manifold of solution environments. LÄS MER