Sökning: "invärtesmedicin"

Visar resultat 11 - 15 av 314 avhandlingar innehållade ordet invärtesmedicin.

  1. 11. Regulation of Tissue Factor and Coagulation Activity : Translation Studies with Focus on Platelet-Monocyte Aggregates and Patients with Acute Coronary Syndrome

    Författare :Christina Christersson; Agneta Siegbahn; Lars Wallentin; Jonas Oldgren; Ingebjorg Seljeflot; Uppsala universitet; []
    Nyckelord :Internal medicine; Myocardial infarction; Coagulation; Platelet-monocyte aggregates; Tissue factor; Thrombin inhibition; Invärtesmedicin;

    Sammanfattning : Myocardial infarction (MI) is often caused by a disruption of an atherosclerotic plaque with activation of coagulation, platelets and inflammation. The aims were; to investigate whether the oral direct thrombin inhibitor, ximelagatran affected markers for coagulation, platelet and inflammation in a patient cohort with recent MI and if the coagulation markers could identify patients with increased risk of new ischemic events; to evaluate some of the mechanisms involved in formation of platelet-monocyte aggregates (PMAs). LÄS MER

  3. 12. Tumour Biological Factors Characterizing Metastasizing Serotonin-producing Ileocaecal Carcinoids

    Författare :Janet Lynn Cunningham; Eva Tiensuu Janson; Kjell Öberg; Irvin M. Modlin; Uppsala universitet; []
    Nyckelord :Internal medicine; endocrine tumour; midgut carcinoid; serotonin-producing neuroendocrine carcinoma; prognosis; morphology; tachykinin; connective tissue growth factor; islet autoantigen-2; morphology; carcinoid syndrome; Invärtesmedicin;

    Sammanfattning : In this study, metastasizing serotonin-producing ileocaecal carcinoid tumours (MSPCs) were examined for biological characteristics that could be used to define clinically relevant subgroups within this patient population. Possible targets for new treatment options were also explored. LÄS MER

  4. 13. Cardiac Troponins in Patients with Suspected or Confirmed Acute Coronary Syndrome : New Applications for Biomarkers in Coronary Artery Disease

    Författare :Kai Eggers; Bertil Lindahl; Stefan James; Paul Collinson; Uppsala universitet; []
    Nyckelord :Internal medicine; Ischemic heart disease; Acute myocardial infarction; Troponin; Natriuretic peptide; CRP; Cystatin C; Artificial neural network; Point of care measurements; Risk prediction; Invärtesmedicin;

    Sammanfattning : The cardiac troponins are the biochemical markers of choice for the diagnosis of acute myocardial infarction (AMI) and risk prediction in patients with acute coronary syndrome (ACS). In this thesis, the role of early serial cardiac troponin I (cTnI) testing was assessed in fairly unselected patient populations admitted because of chest pain and participating in the FAST II-study (n=197) and the FASTER I-study (n=380). LÄS MER

  5. 14. Hyperglycemia and Focal Brain Ischemia : Clinical and Experimental Studies

    Författare :Nasim Farrokhnia; Andreas Terént; Fredrik Lennmyr; Elisabeth Björk; Henrik Hagberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Internal medicine; cerebrovascular disorders; diabetes mellitus; hyperglycemia; infarction; middle cerebral artery; ischemia; mitogen-activated protein kinases; mortality; rats; reactive oxygen species; reperfusion; signal transduction; therapeutics; Invärtesmedicin; Internal medicine; Invärtesmedicin;

    Sammanfattning : Diabetes is a major risk factor for ischemic stroke and is associated with increased mortality. Additionally, hyperglycemia, a common complication in acute stroke, is associated with poor outcome. LÄS MER

  7. 15. Effects of Hemoglobin Normalization with Epoetin in Chronic Kidney Disease

    Författare :Hans Furuland; Björn Wikström; Torbjörn Linde; Peter Barany; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Internal medicine; Anemia; blood viscosity; cardiac output; chronic kidney disease; renal dialysis; dialysis adequacy; erythopoietin; heart rate variability; hemoglobin; hemorheology; hypertension; kidney transplantation; Kt V; left ventricular hypertrophy; Quality of Life; Invärtesmedicin; Internal medicine; Invärtesmedicin;

    Sammanfattning : Anemia is common in patients with chronic kidney disease (CDK), contributes to reduced Quality of Life (QoL) and is associated with cardiovascular disease, morbidity and mortality. Epoetin raises hemoglobin (Hb) and increases QoL and physical exercise capacity. LÄS MER