Sökning: "intracellular replication"

Visar resultat 21 - 25 av 67 avhandlingar innehållade orden intracellular replication.

  1. 21. Survival strategies of Mycobacterium tuberculosis inside the human macrophage

    Författare :Amanda Welin; Maria Lerm; Olle Stendahl; Peter Peters; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Mycobacterium tuberculosis (Mtb) is the bacterium responsible for tuberculosis (TB). For decades, it was believed that TB was a disease of the past, but the onset of the HIV epidemic resulting in a greatly increased number of TB cases, the emergence of antibiotic resistant Mtb strains, and the relative ineffectiveness of the BCG vaccine have put TB back on the agenda. LÄS MER

  3. 22. Host-microbe interactions in coxsackievirus infection : focus on innate immunity

    Författare :Michael Hühn; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Coxsackievirus group B (CVB) is a common virus that usually causes only mild symptoms in humans. However, occasionally these infections result in severe diseases like meningitis, myocarditis and pancreatitis. LÄS MER

  4. 23. In vivo and in vitro models for determination of antiviral activity and resistance

    Författare :Ewa Ljungdahl Ståhle; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The AIDS epidemic has been the driving force for the discovery of substances that inhibit the replication of human immunodeficiency virus (HIV). Much interest has earlier focused on a single gene product central to the life cycle of HIV and to all other retroviruses: the reverse transcriptase (RT), the enzyme responsible for synthesis of DNA from viral RNA. LÄS MER

  5. 24. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes

    Författare :Johanna Raffetseder; Maria Lerm; Olle Stendahl; Vesa Loitto; Trude Helen Flo; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacterium tuberculosis; tuberculosis; macrophage; innate immunity; host-pathogen interaction; antibiotic tolerance; phagosomal maturation; bacterial phenotype; dormancy; persistence; virulence factor; ESAT-6; ESX-1;

    Sammanfattning : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. LÄS MER

  7. 25. Virus Host Interactions in SARS Coronavirus Infection

    Författare :Vithiagaran Gunalan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The global outbreak of Severe Acute Respiratory Syndrome which began in 2002 and ended in 2003 resulted in over 8000 cases in 29 countries, causing an atypical pneumonia which resulted in a case fatality rate of ~10%. The etiological agent of this disease was found to be a novel coronavirus dubbed SARS Coronavirus (SARS-CoV). LÄS MER