Sökning: "intracellular replication"

Visar resultat 11 - 15 av 67 avhandlingar innehållade orden intracellular replication.

  1. 11. Pharmaceutical and mutational interference with virulence of Salmonella enterica serovar typhimurium

    Författare :Aurel Negrea; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Within the species Salmonella enterica are a diverse range of bacteria that can cause illness in humans and many animals. Salmonellae are extremely versatile and can adapt to a variety of environments and hosts. Typhoid and paratyphoid fever, caused by human-restricted S. enterica serovars Typhi and Paratyphi are common in the developing world. LÄS MER

  3. 12. Streptococcus pyogenes : life within the macrophage

    Författare :Erika Hertzén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Streptococcus pyogenes is a versatile human pathogen causing a wide array of diseases ranging from uncomplicated throat and skin infections to invasive life- threatening diseases with a mortality rate of up to 60%. It is ranked number nine on the list of worst infectious diseases world wide, causing 500 000 deaths yearly. LÄS MER

  4. 13. Characterization of HIV-1 RNA and DNA during long-term suppressive therapy

    Författare :Susanne von Stockenström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human immunodeficiency virus (HIV) is the virus causing acquired immune deficiency syndrome (AIDS). Since the discovery of HIV/AIDS over three decades ago, this disease has claimed millions of lives. One of the major accomplishments of modern history came in 1996, when combination antiretroviral therapy (cART) was introduced. LÄS MER

  5. 14. Aspects of immune activation in HIV-1 infection

    Författare :Piotr Nowak; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :immune activation; HMGB1; PHI; HIV-1 LTR-transcription; cytokines; chemokines;

    Sammanfattning : Abnormal immune system activation is central in HIV-1 pathogenesis leading to CD4+ T-cell depletion and inappropriate immune responses. Disease stage and HIV load strongly correlate with the immune activation level which decreases under antiretroviral therapy (ART). LÄS MER

  7. 15. Chemical genetics and immunomodulation in Salmonella enterica serovar typhimurium infection

    Författare :Speranta Banesaru; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Salmonella sp. are versatile bacteria that survive and replicate in a plethora of environmental niches and hosts, including humans. The illnesses caused by various serovars in humans range from mild gastroenteritis to severe systemic disease such as typhoid fever that still cause an important number of casualties especially in developing countries. LÄS MER