Sökning: "intracellular replication"

Visar resultat 1 - 5 av 61 avhandlingar innehållade orden intracellular replication.

  1. 1. The Francisella pathogenicity island its role in type VI secretion and intracellular infection

    Detta är en avhandling från Umeå : Umeå University

    Författare :Lena Meyer; Umeå universitet.; [2015]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella; FPI; Type VI Secretion; Igl; DotU; VgrG; Pdp; microinjection; phagosomal escape; intracellular replication; Clinical Bacteriology; klinisk bakteriologi;

    Sammanfattning : Intracellular bacteria have developed various mechanisms to enter and persist in host cells and, at the same time, to evade the host immune response. One such pathogen is Francisella tularensis, the etiological agent of tularemia. LÄS MER

  2. 2. Regulation of internalization and replication of intracellular bacterial pathogens

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Cell and Molecular Biology

    Författare :Eugénie Bassères; Karolinska Institutet.; Karolinska Institutet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The capacity of intracellular bacteria to cause disease depends on their ability to invade and replicate within eukaryotic host cells. These characteristics also allow preferential invasion and replication by facultative anaerobic bacteria in solid tumours, which can be exploited to design delivery vectors for cancer therapy. LÄS MER

  3. 3. The cell cycle of the hyperthermophilic archaeal genus Sulfolobus

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Karin Hjort; Uppsala universitet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Cell cycle; Sulfolobus; Archaea; Origin; Replication; SIRV2; Mikrobiologi; MEDICINE Microbiology; immunology; infectious diseases; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar; mikrobiologi; Microbiology;

    Sammanfattning : The third domain of life, Archaea is one of the three main evolutionary lineages together with the Bacteria and the Eukarya domains. The archaea are, despite their prokaryotic cell organisation, more closely related to eukaryotes than to bacteria in terms of the informational pathways (DNA replication, transcription and translation). LÄS MER

  4. 4. Mechanisms of the intracellular survival of Francisella tularensis

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Linda Tancred; Umeå universitet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; Igl; MglA; J774; IFN-γ; RNS; ROS; phagosome; MEDICINE Microbiology; immunology; infectious diseases Microbiology Clinical bacteriology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Mikrobiologi Klinisk bakteriologi; mikrobiologi; Microbiology;

    Sammanfattning : Francisella tularensis is a gram-negative, highly virulent, intracellular bacterium which causes the zoonotic disease tularemia. The subspecies tularensis and holarctica are clinically important, and the former is the more virulent. The intracellular lifestyle of F. LÄS MER

  5. 5. Intracellular pathways involved in formation and degradation of prions

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Neuroscience

    Författare :Elin Allard; Karolinska Institutet.; Karolinska Institutet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Prions cause invariably fatal neurodegenerative diseases, in which a misfolded host-encoded protein appears to be the main, if not the only, component of the infectious agent. During disease, a normal cellular protein, PrPC, is converted to a disease-related isoform, PrPSc, by a post-translational process that might require auxiliary cellular cofactors. LÄS MER