Avancerad sökning

Hittade 4 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Early detection of major surgical postoperative complications evaluated by microdialysis

    Författare :Tal Hörer; Kjell Janson; Lars Norgren; Bengt Jeppsson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aortic occlusion balloon; anastomotic leakage; glycerol; intraabdominal hypertension; intraperitoneal microdialysis; intestinal ischemia; intraabdominal metabolism; lactate pyruvate ratio; postoperative complications; ruptured abdominal aortic anerusym; Kirurgi; Surgery;

    Sammanfattning : Major abdominal surgery may be followed by postoperative complications, especially in the elderly and patients with co morbidities as diabetes mellitus and obesity. Some of the most feared complications as anastomotic leakage, abdominal infections, abdominal compartment syndrome (ACS) and intestinal ischemia can lead to sepsis, systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) with high morbidity and mortality. LÄS MER

  3. 2. Insulin resistance in pancreatic cancer

    Författare :Bengt Isaksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Pancreatic cancer; glucose transport; glucose metabolism; insulin signaling; insulin resistance; uncoupling proteins; obstructive jaundice; IAPP; risk factors.;

    Sammanfattning : The dismal prognosis of pancreatic cancer (PC) is related to metabolic complications of the tumor. Impaired glucose tolerance or diabetes due to insulin resistance, and cachexia are observed early and frequently in these patients. The basic mechanisms of PC-associated insulin resistance and weight loss are not fully understood. LÄS MER

  4. 3. The gastrointestinal tract in cardiac anaesthesia and intensive care : Clinical and experimental studies

    Författare :Jenny Seilitz; Kristofer Nilsson; Kjell Jansson; Birger Axelsson; Måns Edström; Sten Rubertsson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute Gastrointestinal Injury grade; biomarkers; extracorporeal circulation; splanchnic perfusion; inotropic drugs; vasoactive drugs; lactate; lactate pyruvate ratio;

    Sammanfattning : Gastrointestinal (GI) complications after cardiac surgery have a substantial impact on outcome. The aims were to investigate the frequency of, and methods for detecting, GI dysfunction after cardiac surgery and its relation to outcome, and the impact of vasoactive drugs on the GI tract in experimental cardiogenic shock. LÄS MER

  5. 4. Transcriptional activity of PPARγ in primary human adipocytes

    Författare :Lilian Sauma; Fredrik Nyström; Mats Söderström; Jan Eriksson; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The prevalence of obesity is increasing in most parts of the world and is a strong risk factor for the development of insulin resistance, type 2 diabetes and hypertension. Adipose tissue is mainly composed of adipocytes which store energy in the form of triglycerides and release it as free fatty acids. LÄS MER