Sökning: "interstitial glycerol"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden interstitial glycerol.

  1. 1. Insulin resistance in skeletal muscle. With special reference to interstitial insulin and glycerol

    Författare :Mikaela Sjöstrand; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insulin resistance; skeletal muscle; microdialysis; interstitial insulin; interstitial glycerol;

    Sammanfattning : Insulin resistance is a central feature of type 2 diabetes and obesity and is associated with cardiovascular disease. In insulin-resistant muscle, the insulin-mediated glucose uptake is decreased.The delivery of insulin to the interstitial fluid of human skeletal muscle has previously not been investigated. LÄS MER

  3. 2. Myocardial ischemia-reperfusion and cardioprotection. A study with microdialysis in a porcine model

    Författare :Carsten Metzsch; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; heart preservation; metoprolol; levosimendan; beta-blockers; pharmacological preconditioning; myocardial ischemia; cardioprotection; glycerol; microdialysis; cold cardioplegic storage;

    Sammanfattning : The studies in this thesis are based on questions raised in the clinical setting. Perioperative myocardial ischemia occurs more often than recognized. This may lead to myocardial infarction, increased morbidity, mortality, and health care costs. LÄS MER

  4. 3. Microdialysis and Intensive Care. Clinical and experimental studies

    Författare :Per Ederoth; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology; traumatic brain injury; glucose; glycerol; lipolysis; epidural; postoperative analgesia; experimental pancreatitis; human; blood-brain barrier; morphine; pharmacokinetics; Microdialysis; intensive care; Anestesiologi; intensivvård;

    Sammanfattning : Microdialysis was used to monitor local concentrations of energy metabolites in different organs, and to study the pharmacokinetics of morphine over the blood-brain barrier in intact and injured brain tissue in conditions treated in the Intensive Care Unit. After major abdominal or thoracoabdominal surgery, postoperative thoracic epidural analgesia resulted in higher glycerol concentrations in the deltoid subcutaneous adipose tissue, implying increased lipolysis, on the third postoperative day as compared to intravenous infusion of morphine, possibly due to a locally increased sympathetic tone. LÄS MER

  5. 4. Bedside monitoring of cerebral energy metabolism using intracerebral microdialysis during neuro intensive care

    Författare :Nils Ståhl; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; neurofysiologi; Neurologi; neuropsychology; Neurology; glycerol.; glutamate; pyruvate; lactate; glucose; hyperglycaemia; intensive care; brain injury; Human; cerebral microdialysis; neurophysiology;

    Sammanfattning : In clinical situations with raised intracranial pressure (ICP) and impending insufficient cerebral blood flow (ischaemia), bedside information about energy metabolism in the brain would be helpful. Microdialysis is a technique that makes it possible to monitor the interstitial concentrations of various compounds in an organ. LÄS MER

  7. 5. Sampling from a suction induced mini-erosion in human skin. Methodological studies

    Författare :Christer Svedman; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular permeability; neurogenic inflammation; glucose; diabetes mellitus; interstitial fluid; transdermal; skin; sampling; Medicine human and vertebrates ; Medicin människa och djur ;

    Sammanfattning : Dermal interstitial fluid (IF) was extracted serially and painlessly by brief suction for as long as 6 days. The erosion was otherwise kept occluded, Sample volumes exceded those required for measuring a wide range of biological substances. Epidermal regeneration was rapid. LÄS MER