Sökning: "integrin alpha2beta1"
Hittade 5 avhandlingar innehållade orden integrin alpha2beta1.
1. Effects of c-erbB2 signaling on morphogenesis and cell adhesion in mammary epithelial cells
Sammanfattning : .... LÄS MER
2. Chondrocyte-matrix interactions: with emphasis on the collagen binding integrin a10ß1
Sammanfattning : The work in this thesis has been focused on chondrocyte integrins and their interaction with the matrix proteins chondroadherin (CHAD) and collagen type II (CII). Affinity purification of CHAD-binding proteins from chondrocyte lysate, followed by immunoprecipitation of EDTA-eluted material identified alpha2beta1 as a CHAD-binding integrin. LÄS MER
3. Studies on chondrocyte integrins and mechanical signaling
Sammanfattning : Integrins are a family of cell surface receptors known to bind matrix proteins and to mediate signals such as mechanical signals between the cell and the surrounding matrix. We have studied integrins that are expressed by chondrocytes, with specific focus on the integrins that interact with the cartilage matrix protein collagen type II. LÄS MER
4. Non-enveloped virus infection probed with host cellular molecules : a structural study
Sammanfattning : Early steps in virus replication require binding of the virus to its target cell, entry into the cell, and delivery of the viral genome into the cell in order to gain access to the cellular macromolecular synthesis machinery. This infectious process can only be initiated if the virus successfully attaches to a specific receptor on the plasma membrane of the target cell. LÄS MER
5. Studies of cell migration and matrix protease production in human lung cancer cell lines
Sammanfattning : Metastatic spread in cancer is a complex multistep process involving continuous, sequential interactions between tumour cells and their respective microenvironment. Invasiveness per se has not been studied in this thesis, only some of its major components, such as cell migration and matrix protease production. LÄS MER
